Tdark ZNF302 Zinc finger protein 302

Protein Summary

Description

May be involved in transcriptional regulation. This gene encodes a member of the zinc-finger protein family. The encoded protein contains seven C2H2-type zinc fingers and a KRAB domain, but its function has yet to be determined. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2014]

Uniprot Accession IDs

• Q9NR11
• Q658J3
• Q9BZD8
• Q9P0J4

Gene Name

• ZNF302

Ensembl ID

• ENST00000423823
• ENSP00000405219
• ENSG00000089335
• ENST00000457781
• ENSP00000391067
• ENST00000505242
• ENSP00000421028

Symbol

• ZNF135L
• ZNF140L
• ZNF327
• HSD16
• MST154
• ZNF327
• MSTP154
• ZNF135L
• ZNF140L

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.73
PubMedID	0.65
cell line	0.59
protein domain	0.58
tissue sample	0.56

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.39   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 107   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.39   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Expression Data (0 Tissues)

tutorial

No expression data found

Protein Sequence and Structure

Residue Counts

Protein Sequence

Find Targets by Sequence

Show Full Sequence

ProtVista Viewer

Related Tools (3)

GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

Go To Tool

GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

Go To Tool

ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

Go To Tool

Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (10)

Explore Interacting Targets

1 – 10 of 10

• See Interactions on String-DB

VWCE

Tbio

Novelty:  0.09328341

p_int:  0.999983725

p_ni:  2.5e-8

p_wrong:  0.00001625

Data Source:  BioPlex

TMEM25

Tdark

Novelty:  0.35505784

p_int:  0.986158615

p_ni:  0.013718839

p_wrong:  0.000122546

Data Source:  BioPlex

RFPL4B

Tdark

Novelty:  2.42779597

p_int:  0.945127691

p_ni:  4.1e-8

p_wrong:  0.054872268

Score:  0.201

Data Source:  BioPlex,STRINGDB

DMC1

Tbio

Novelty:  0.05445277

p_int:  0.864281735

p_ni:  0.135717576

p_wrong:  6.89e-7

Score:  0.327

Data Source:  BioPlex,STRINGDB

TRIM28

Tbio

Family:  Epigenetic

Novelty:  0.00778381

Score:  0.903

Data Source:  STRINGDB

ANKRA2

Tbio

Novelty:  0.19358401

Score:  0.542

Data Source:  STRINGDB

ZFYVE16

Tbio

Novelty:  0.10765234

Score:  0.53

Data Source:  STRINGDB

SCGB2B2

Tdark

Novelty:  0.80383495

Score:  0.44

Data Source:  STRINGDB

UBA2

Tbio

Novelty:  0.01582807

Score:  0.401

Data Source:  STRINGDB

LSM14A

Tbio

Novelty:  0.04728617

Score:  0.4

Data Source:  STRINGDB

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (4)

Reactome (3)

KEGG (1)

Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets

Items per page:

5

1 – 3 of 3

Data Source	Name	Explore in Pharos	Explore in Source
Reactome	Gene expression (Transcription)	1452 targets	R-HSA-74160
Reactome	Generic Transcription Pathway	1195 targets	R-HSA-212436
Reactome	RNA Polymerase II Transcription	1314 targets	R-HSA-73857

Name	Explore in Pharos	Explore in Source
Gene expression (Transcription)	1452 targets	R-HSA-74160
Generic Transcription Pathway	1195 targets	R-HSA-212436
RNA Polymerase II Transcription	1314 targets	R-HSA-73857

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (4)

Functions (3)

Components (1)

Find Similar Targets

Items per page:

10

1 – 3 of 3

GO Term	Evidence	Assigned by
DNA-binding transcription factor activity, RNA polymerase II-specific	Inferred from Sequence Alignment (ISA)	NTNU_SB
DNA binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW
metal ion binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW

Disease Associations (null)

No disease associations found

GWAS Traits (0)

No GWAS traits found

Find similar targets by:

UniProt Keyword Find Similar Targets

No Header	No Header
Alternative splicing
Complete proteome
DNA-binding
Isopeptide bond
Metal-binding
Nucleus
Reference proteome
Repeat
Transcription
Transcription regulation

IDG Resources

No IDG generated resources found

Orthologs (1)

1 – 1 of 1

Species	Name	Source ID	Gene ID	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 181		744102

Species	Name	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 181

Publication Statistics

PubMed Score 1.39

PubMed score by year

Reset Zoom

PubTator Score 0.92

PubTator score by year

Reset Zoom

Related Publications

Text Mined References (8)

Items per page:

10

0 of 0

PMID	Year	Title