You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
ZNF296
Zinc finger protein 296

Protein Summary
Description
May be a transcriptional corepressor with KLF4.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000303809
  • ENSP00000302770
  • ENSG00000170684

Symbol
  • ZNF342
  • ZFP296
  • ZNF342
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.84
cell line
0.63
PubMedID
0.63
transcription factor binding site profile
0.63
transcription factor
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.3   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.3   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (37)
MBD3L1
Tbio
Novelty:  0.11297566
p_int:  0.999999278
p_ni:  4.7e-7
p_wrong:  2.52e-7
Score:  0.465
Data Source:  BioPlex,STRINGDB
L3MBTL2
Tbio
Family:  Epigenetic
Novelty:  0.11193867
p_int:  0.995612976
p_ni:  1.82e-7
p_wrong:  0.004386841
Score:  0.224
Data Source:  BioPlex,STRINGDB
MPO
Tchem
Family:  Enzyme
Novelty:  0.00020698
Score:  0.72
Data Source:  STRINGDB
NKPD1
Tdark
Family:  Enzyme
Novelty:  0.77385086
Score:  0.679
Data Source:  STRINGDB
KHDC3L
Tbio
Novelty:  0.0343295
Score:  0.608
Data Source:  STRINGDB
CLASRP
Tbio
Novelty:  0.00582947
Score:  0.605
Data Source:  STRINGDB
ERAS
Tbio
Family:  Enzyme
Novelty:  0.01270165
Score:  0.593
Data Source:  STRINGDB
LEUTX
Tdark
Family:  TF
Novelty:  0.20538904
Score:  0.586
Data Source:  STRINGDB
NR0B1
Tbio
Family:  NR
Novelty:  0.00166563
Score:  0.579
Data Source:  STRINGDB
CLPTM1
Tbio
Novelty:  0.06426049
Score:  0.563
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (10)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (30)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Alzheimer disease
3
15
0
7.6
98.1
family history of Alzheimer’s disease
1
12
0
7.8
97.4
total cholesterol measurement
9
14
22
95.4
low density lipoprotein cholesterol measurement
31
19
59
94.7
high density lipoprotein cholesterol measurement
9
4
9
91.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Alzheimer disease
0
7.6
98.1
family history of Alzheimer’s disease
0
7.8
97.4
total cholesterol measurement
22
95.4
low density lipoprotein cholesterol measurement
59
94.7
high density lipoprotein cholesterol measurement
9
91.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 296
468915
Mouse
MGI:1926956
63872
Rat
RGD:1595818
365511
Dog
zinc finger protein 296
VGNC:48692
484453
Horse
zinc finger protein 296 [Source:HGNC Symbol;Acc:HGNC:15981]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 296
Mouse
Rat
Dog
zinc finger protein 296
Horse
zinc finger protein 296 [Source:HGNC Symbol;Acc:HGNC:15981]
Publication Statistics
PubMed Score 6.30
PubMed score by year
PubTator Score 1.74
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title