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Tdark
ZNF276
Zinc finger protein 276

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000289816
  • ENSP00000289816
  • ENSG00000158805
  • ENST00000443381
  • ENSP00000415836

Symbol
  • CENP-Z
  • ZFP276
  • ZNF477
  • ZADT
  • CENPZ
  • CENP-Z
  • ZFP276
  • ZNF477
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.83
transcription factor
0.68
transcription factor binding site profile
0.64
tissue sample
0.63
histone modification site profile
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.76   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 124   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.76   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 124   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (53)
SHCBP1
Tbio
Novelty:  0.09160318
p_int:  0.999987696
p_ni:  0.000012304
Data Source:  BioPlex
DHPS
Tchem
Family:  Enzyme
Novelty:  0.00776893
p_int:  0.999540755
p_ni:  0.000459245
Data Source:  BioPlex
PBX4
Tbio
Family:  TF
Novelty:  0.09471693
p_int:  0.999264118
p_ni:  0.000735877
p_wrong:  5e-9
Data Source:  BioPlex
NCOR1
Tchem
Family:  TF
Novelty:  0.0021926
p_int:  0.994814293
p_ni:  0.005185707
Score:  0.185
Data Source:  BioPlex,STRINGDB
PPP2R5E
Tbio
Family:  Enzyme
Novelty:  0.05974697
p_int:  0.9932057
p_ni:  0.006794296
p_wrong:  4e-9
Data Source:  BioPlex
TBL1XR1
Tbio
Novelty:  0.00503043
p_int:  0.984026581
p_ni:  0.014667957
p_wrong:  0.001305462
Data Source:  BioPlex
SOGA3
Tdark
Novelty:  2.17187131
p_int:  0.983995627
p_ni:  0.000890002
p_wrong:  0.015114371
Data Source:  BioPlex
DCAF1
Tbio
Novelty:  0.0170232
p_int:  0.875860869
p_ni:  0.124139131
Data Source:  BioPlex
LTV1
Tbio
Novelty:  0.04050879
p_int:  0.794360072
p_ni:  0.205639928
Data Source:  BioPlex
ZNF827
Tdark
Family:  TF
Novelty:  0.22115243
Score:  0.78
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (54)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hair color
5
12
1
4.1
99.8
5
2
0
1.7
98.3
suntan
1
7
7
98.3
homocysteine measurement
2
3
3
98.3
glomerular filtration rate
9
6
8
5.5
96.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hair color
1
4.1
99.8
0
1.7
98.3
suntan
7
98.3
homocysteine measurement
3
98.3
glomerular filtration rate
8
5.5
96.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 276
VGNC:13816
454324
Macaque
zinc finger protein 276
699603
Mouse
MGI:1888495
57247
Rat
RGD:1307469
307924
Dog
zinc finger protein 276
VGNC:48685
489653
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 276
Macaque
zinc finger protein 276
Mouse
Rat
Dog
zinc finger protein 276
Publication Statistics
PubMed Score 3.76
PubMed score by year
PubTator Score 1.33
PubTator score by year
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Related Publications
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PMID
Year
Title