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Tdark
ZNF264
Zinc finger protein 264

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a zinc finger protein and belongs to the krueppel C2H2-type zinc-finger protein family. Zinc finger proteins are often localized in the nucleus, bind nucleic acids, and regulate transcription. [provided by RefSeq, Jan 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263095
  • ENSP00000263095
  • ENSG00000083844
  • ENST00000536056
  • ENSP00000440376

Symbol
  • KIAA0412
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.74
protein domain
0.58
co-expressed gene
0.57
cell line
0.56
histone modification site profile
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.19   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.19   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
ZYG11A
Tbio
Novelty:  0.13413639
p_int:  0.999993891
p_ni:  0.000006098
p_wrong:  1e-8
Score:  0.189
Data Source:  BioPlex,STRINGDB
CENPB
Tbio
Novelty:  0.0036225
p_int:  0.999993266
p_ni:  0.000006734
Data Source:  BioPlex
TRIM24
Tchem
Family:  Epigenetic
Novelty:  0.00532747
p_int:  0.99996793
p_ni:  0.00003207
Score:  0.173
Data Source:  BioPlex,STRINGDB
GOPC
Tbio
Novelty:  0.01110168
p_int:  0.99983554
p_ni:  0.00016446
Data Source:  BioPlex
ZNF805
Tdark
Family:  TF
Novelty:  2.14559387
p_int:  0.999023195
p_ni:  1e-9
p_wrong:  0.000976804
Score:  0.408
Data Source:  BioPlex,STRINGDB
TRIM41
Tbio
Family:  Enzyme
Novelty:  0.17238173
p_int:  0.993208093
p_ni:  0.00679155
p_wrong:  3.57e-7
Score:  0.172
Data Source:  BioPlex,STRINGDB
TRIM39
Tbio
Family:  Enzyme
Novelty:  0.0837441
p_int:  0.983537905
p_ni:  0.016462074
p_wrong:  2.1e-8
Score:  0.173
Data Source:  BioPlex,STRINGDB
ZNF460
Tdark
Family:  TF
Novelty:  0.71547663
p_int:  0.97868185
p_ni:  0.021317515
p_wrong:  6.35e-7
Score:  0.313
Data Source:  BioPlex,STRINGDB
SORL1
Tbio
Novelty:  0.00380895
p_int:  0.958098818
p_ni:  0.041901182
Data Source:  BioPlex
ERBIN
Tbio
Novelty:  0.01419561
p_int:  0.950936521
p_ni:  0.049063479
Score:  0.333
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Dupuytren Contracture
2
1
0
1.3
68.6
heel bone mineral density
2
1
2
57.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Dupuytren Contracture
0
1.3
68.6
heel bone mineral density
2
57.8
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 264
VGNC:2184
100615409
Macaque
zinc finger protein 805 [Source:HGNC Symbol;Acc:HGNC:23272]
Dog
zinc finger protein 264 [Source:HGNC Symbol;Acc:HGNC:13057]
Horse
zinc finger protein 264
100059529
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 264
Macaque
zinc finger protein 805 [Source:HGNC Symbol;Acc:HGNC:23272]
Dog
zinc finger protein 264 [Source:HGNC Symbol;Acc:HGNC:13057]
Horse
zinc finger protein 264
Publication Statistics
PubMed Score 4.19
PubMed score by year
PubTator Score 0.79
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title