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Tbio
ZNF263
Zinc finger protein 263

Protein Summary
Description
Might play an important role in basic cellular processes as a transcriptional repressor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000219069
  • ENSP00000219069
  • ENSG00000006194

Symbol
  • FPM315
  • ZKSCAN12
  • FPM315
  • ZSCAN44
  • ZKSCAN12
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
histone modification site profile
0.84
transcription factor binding site profile
0.84
virus perturbation
0.72
tissue sample
0.69


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 211   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 211   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (79)
ZNF397
Tbio
Family:  TF
Novelty:  0.60034816
p_int:  0.99999999
p_ni:  1e-8
Score:  0.693
Data Source:  BioPlex,STRINGDB
VPS39
Tbio
Novelty:  0.02172601
p_int:  0.999998422
p_ni:  0.000001577
p_wrong:  1e-9
Score:  0.169
Data Source:  BioPlex,STRINGDB
TWNK
Tbio
Novelty:  0.00393371
p_int:  0.999987745
p_ni:  0.000012255
Data Source:  BioPlex
ZSCAN20
Tdark
Family:  TF
Novelty:  0.37441538
p_int:  0.999986035
p_ni:  0.000013964
p_wrong:  1e-9
Score:  0.653
Data Source:  BioPlex,STRINGDB
NKTR
Tbio
Novelty:  0.01287691
p_int:  0.999969458
p_ni:  0.000030542
Data Source:  BioPlex
NFX1
Tbio
Family:  TF
Novelty:  0.0284509
p_int:  0.999967036
p_ni:  0.000009836
p_wrong:  0.000023128
Score:  0.158
Data Source:  BioPlex,STRINGDB
AHCYL2
Tbio
Family:  Enzyme
Novelty:  0.08695339
p_int:  0.999960079
p_ni:  0.000039921
Data Source:  BioPlex
TRIM41
Tbio
Family:  Enzyme
Novelty:  0.17238173
p_int:  0.999867455
p_ni:  0.0001325
p_wrong:  4.5e-8
Score:  0.168
Data Source:  BioPlex,STRINGDB
RPS27A
Tbio
Novelty:  0.00658124
p_int:  0.999762967
p_ni:  0.000237032
p_wrong:  1e-9
Score:  0.2
Data Source:  BioPlex,STRINGDB
SCAND1
Tbio
Novelty:  0.06863895
p_int:  0.999756749
p_ni:  0.000212256
p_wrong:  0.000030995
Score:  0.384
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

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Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Sequence Alignment (ISA)
NTNU_SB
Traceable Author Statement (TAS)
ProtInc
Inferred by Curator (IC)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
4.8
54.4
heel bone mineral density
1
1
1
30.2
mean corpuscular volume
1
1
1
10.6
gut microbiome measurement
1
1
0
5.5
0.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
4.8
54.4
heel bone mineral density
1
30.2
mean corpuscular volume
1
10.6
gut microbiome measurement
0
5.5
0.9
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 263
VGNC:5963
453860
Macaque
zinc finger protein 263
702166
Mouse
MGI:1921370
74120
Rat
RGD:1307301
287076
Dog
zinc finger protein 263
VGNC:48683
490040
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 263
Macaque
zinc finger protein 263
Mouse
Rat
Dog
zinc finger protein 263
Publication Statistics
PubMed Score 10.00
PubMed score by year
PubTator Score 4.73
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title