Tdark ZNF232 Zinc finger protein 232

Protein Summary

Description

May be involved in transcriptional regulation.

Uniprot Accession IDs

• Q9UNY5

Gene Name

• ZNF232

Ensembl ID

• ENST00000250076
• ENSP00000250076
• ENSG00000167840

Symbol

• ZSCAN11
• ZSCAN11

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.73
kinase perturbation	0.6
histone modification site profile	0.56
transcription factor perturbation	0.54
molecular function	0.42

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.68   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 177   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.68   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 177   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Protein Sequence and Structure

Residue Counts

Protein Sequence

Find Targets by Sequence

Show Full Sequence

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Expression Data (0 Tissues)

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No expression data found

Related Tools

Target Illumination GWAS Analytics (TIGA)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

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GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

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GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

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ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

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Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (54)

Explore Interacting Targets

1 – 10 of 54

• See Interactions on String-DB

ZBED9

Tdark

Novelty:  0.3335355

p_int:  0.999999995

p_wrong:  5e-9

Score:  0.699

Data Source:  BioPlex,STRINGDB

TRIO

Tbio

Family:  Kinase

Novelty:  0.03113573

p_int:  0.999999971

p_ni:  2.9e-8

Score:  0.238

Data Source:  BioPlex,STRINGDB

ZSCAN20

Tdark

Family:  TF

Novelty:  0.37441538

p_int:  0.999999914

p_ni:  8.6e-8

Score:  0.653

Data Source:  BioPlex,STRINGDB

ZKSCAN5

Tdark

Family:  TF

Novelty:  0.09717066

p_int:  0.999999891

p_wrong:  1.09e-7

Score:  0.747

Data Source:  BioPlex,STRINGDB

P3H2

Tbio

Family:  Enzyme

Novelty:  0.04237396

p_int:  0.999999868

p_ni:  1.32e-7

Data Source:  BioPlex

ZKSCAN4

Tbio

Family:  TF

Novelty:  0.33154485

p_int:  0.999999867

p_ni:  1.33e-7

Score:  0.679

Data Source:  BioPlex,STRINGDB

ZNF397

Tbio

Family:  TF

Novelty:  0.60034816

p_int:  0.999999772

p_ni:  2.28e-7

Score:  0.696

Data Source:  BioPlex,STRINGDB

ZSCAN30

Tdark

Family:  TF

Novelty:  1.6056338

p_int:  0.99999939

p_ni:  6.07e-7

p_wrong:  3e-9

Score:  0.686

Data Source:  BioPlex,STRINGDB

ZKSCAN3

Tbio

Family:  TF

Novelty:  0.06833314

p_int:  0.999999249

p_ni:  7.51e-7

Score:  0.691

Data Source:  BioPlex,STRINGDB

ZNF446

Tdark

Family:  TF

Novelty:  0.80369039

p_int:  0.999996734

p_ni:  0.000003266

Score:  0.555

Data Source:  BioPlex,STRINGDB

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (6)

Functions (3)

Components (3)

Find Similar Targets

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10

1 – 3 of 3

GO Term	Evidence	Assigned by
DNA-binding transcription factor activity, RNA polymerase II-specific	Inferred from Sequence Alignment (ISA)	NTNU_SB
DNA binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW
metal ion binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW

Disease Associations ()

No disease associations found

GWAS Traits (4)

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 4 of 4

GWAS Trait	EFO ID	Study Count	SNP Count	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
mean corpuscular volume	EFO_0004526	1	1	1		78.9
Keratoconus	Orphanet_156071	1	1	1		61.4
age at first sexual intercourse measurement	EFO_0009749	1	1	1		14.2
family history of Alzheimer’s disease	EFO_0009268	1	1	0	1.1	2.7

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 4 of 4

GWAS Trait	EFO ID	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
mean corpuscular volume	EFO_0004526	1		78.9
Keratoconus	Orphanet_156071	1		61.4
age at first sexual intercourse measurement	EFO_0009749	1		14.2
family history of Alzheimer’s disease	EFO_0009268	0	1.1	2.7

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Find similar targets by:

UniProt Keyword Find Similar Targets

No Header	No Header
Alternative splicing
Complete proteome
DNA-binding
Metal-binding
Nucleus
Polymorphism
Reference proteome
Repeat
Transcription
Transcription regulation

GWAS Trait Find Similar Targets

No Header	No Header
age at first sexual intercourse measurement
family history of Alzheimer’s disease
Keratoconus
mean corpuscular volume

IDG Resources

No IDG generated resources found

Orthologs (2)

1 – 2 of 2

Species	Name	Source ID	Gene ID	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 232	VGNC:9805	455260
Pig	zinc finger protein 232		100514871

Species	Name	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 232
Pig	zinc finger protein 232

Publication Statistics

PubMed Score 1.68

PubMed score by year

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PubTator Score 1.20

PubTator score by year

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Related Publications

Text Mined References (8)

Items per page:

10

0 of 0

PMID	Year	Title