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Tbio
ZNF2
Zinc finger protein 2

Protein Summary
Description
May be involved in transcriptional regulation. The protein encoded by this gene belongs to the C2H2-type zinc-finger protein family. The exact function of this gene is not known, however, zinc-finger proteins are known to interact with DNA and function as transcription regulators. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000614034
  • ENSP00000480297
  • ENSG00000275111

Symbol
  • ZNF661
  • A1-5
  • ZNF661
  • Zfp661
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.69
microRNA
0.64
virus perturbation
0.64
transcription factor binding site profile
0.63
cell type or tissue
0.61


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 99.46   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 99.46   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (88)
PUM3
Tbio
Novelty:  0.02344206
p_int:  0.99252828
p_ni:  0.00747172
Score:  0.183
Data Source:  BioPlex,STRINGDB
ZFP62
Tdark
Family:  TF
Novelty:  0.17608098
p_int:  0.992273414
p_ni:  0.007726586
Score:  0.214
Data Source:  BioPlex,STRINGDB
TAF1B
Tbio
Family:  Enzyme
Novelty:  0.10174314
p_int:  0.991380022
p_ni:  0.008619885
p_wrong:  9.4e-8
Score:  0.201
Data Source:  BioPlex,STRINGDB
ZNF800
Tdark
Family:  TF
Novelty:  0.53546034
p_int:  0.990880889
p_ni:  0.009110318
p_wrong:  0.000008793
Data Source:  BioPlex
RRP8
Tbio
Family:  Enzyme
Novelty:  0.04922797
p_int:  0.990304587
p_ni:  0.009695413
Score:  0.261
Data Source:  BioPlex,STRINGDB
BUD13
Tbio
Novelty:  0.05228416
p_int:  0.989197465
p_ni:  0.010802522
p_wrong:  1.3e-8
Data Source:  BioPlex
RPF2
Tbio
Novelty:  0.04148504
p_int:  0.983312789
p_ni:  0.016687211
Data Source:  BioPlex
ZNF770
Tdark
Family:  TF
Novelty:  0.79192428
p_int:  0.978378577
p_ni:  0.021621419
p_wrong:  4e-9
Data Source:  BioPlex
GLYR1
Tbio
Family:  Epigenetic
Novelty:  0.036121
p_int:  0.97401479
p_ni:  0.02598521
Score:  0.252
Data Source:  BioPlex,STRINGDB
RPL37A
Tbio
Novelty:  0.03475061
p_int:  0.97302864
p_ni:  0.02697135
p_wrong:  1.1e-8
Score:  0.455
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1919430
72180
Horse
zinc finger protein 2
VGNC:25274
100062975
Cow
zinc finger protein 2
VGNC:37221
539022
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Horse
zinc finger protein 2
Cow
zinc finger protein 2
Publication Statistics
PubMed Score 99.46
PubMed score by year
PubTator Score 38.28
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title