Tbio ZNF154 Zinc finger protein 154

Protein Summary

Description

May be involved in transcriptional regulation. This gene encodes a protein that belongs to the zinc finger Kruppel family of transcriptional regulators, whose members are thought to function in normal and abnormal cell growth and differentiation. Hypermethylation of this gene is associated with the recurrence of non muscle invasive bladder cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Uniprot Accession IDs

• Q13106
• A7MCY3
• Q8IVG7
• Q8NAR0

Gene Name

• ZNF154

Ensembl ID

• ENST00000451275
• ENSP00000469633
• ENSG00000179909
• ENST00000512439
• ENSP00000421258

Symbol

• KIAA2003
• pHZ-92

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.58
tissue sample	0.54
cell type or tissue	0.52
cell line	0.5
co-expressed gene	0.48

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.92   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 88   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.92   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0