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Tdark
ZNF142
Zinc finger protein 142

Protein Summary
Description
May be involved in transcriptional regulation. The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins. It contains 31 C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000411696
  • ENSP00000398798
  • ENSG00000115568
  • ENST00000449707
  • ENSP00000408643

Symbol
  • KIAA0236
  • HA4654
  • pHZ-49
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.89
transcription factor binding site profile
0.74
tissue sample
0.64
cell type or tissue
0.63
cell line
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.24   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 23   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.24   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
CACNG5
Tdark
Family:  IC
Novelty:  0.52705448
p_int:  0.999981943
p_ni:  0.000017992
p_wrong:  6.5e-8
Score:  0.188
Data Source:  BioPlex,STRINGDB
FBLN2
Tbio
Novelty:  0.01340024
p_int:  0.979762868
p_ni:  0.010908051
p_wrong:  0.009329082
Data Source:  BioPlex
RPL30
Tbio
Novelty:  0.0134194
p_int:  0.813719787
p_ni:  0.000212668
p_wrong:  0.186067545
Score:  0.183
Data Source:  BioPlex,STRINGDB
RUFY4
Tbio
Novelty:  0.95990073
Score:  0.732
Data Source:  STRINGDB
CDK5R2
Tbio
Family:  Enzyme
Novelty:  0.16247335
Score:  0.721
Data Source:  STRINGDB
C16orf96
Tdark
Novelty:  6.8192769
Score:  0.713
Data Source:  STRINGDB
OR51Q1
Tdark
Family:  oGPCR
Novelty:  5.05719446
Score:  0.712
Data Source:  STRINGDB
GLB1L
Tdark
Family:  Enzyme
Novelty:  0.43027328
Score:  0.694
Data Source:  STRINGDB
BCS1L
Tbio
Family:  Enzyme
Novelty:  0.01764582
Score:  0.687
Data Source:  STRINGDB
SLC38A11
Tdark
Family:  Transporter
Novelty:  0.31184686
Score:  0.681
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (14)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
3
3
3
85.7
hemoglobin measurement
3
3
3
82.2
reticulocyte count
1
1
1
65.5
body mass index
2
1
2
61.8
diastolic blood pressure
1
1
1
61.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
3
85.7
hemoglobin measurement
3
82.2
reticulocyte count
1
65.5
body mass index
2
61.8
diastolic blood pressure
1
61.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 142
VGNC:14167
459945
Macaque
zinc finger protein 142
702214
Mouse
MGI:1924514
77264
Rat
RGD:1309648
316524
Dog
zinc finger protein 142
VGNC:48660
488524
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 142
Macaque
zinc finger protein 142
Mouse
Rat
Dog
zinc finger protein 142
Publication Statistics
PubMed Score 5.24
PubMed score by year
PubTator Score 0.39
PubTator score by year
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Related Publications
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PMID
Year
Title