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Tbio
ZNF135
Zinc finger protein 135

Protein Summary
Description
Plays a role in the regulation of cell morphology and cytoskeletal organization. May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000313434
  • ENSP00000321406
  • ENSG00000176293
  • ENST00000359978
  • ENSP00000369437
  • ENST00000401053
  • ENSP00000441410
  • ENST00000511556
  • ENSP00000422074

Symbol
  • ZNF61
  • ZNF78L1
  • pT3
  • ZNF61
  • pHZ-17
  • ZNF78L1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.6
protein domain
0.58
tissue
0.58
cellular component
0.49
histone modification site profile
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 496.92   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 77   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 496.92   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (10)
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.903
Data Source:  STRINGDB
F2
Tclin
Family:  Enzyme
Novelty:  0.00004833
Score:  0.669
Data Source:  STRINGDB
HTN3
Tbio
Novelty:  0.00825966
Score:  0.644
Data Source:  STRINGDB
ITPRID1
Tdark
Novelty:  2.36881208
Score:  0.496
Data Source:  STRINGDB
PTS
Tbio
Family:  Enzyme
Novelty:  0.00279396
Score:  0.491
Data Source:  STRINGDB
LRRIQ1
Tdark
Novelty:  1.8251367
Score:  0.486
Data Source:  STRINGDB
BRD8
Tbio
Family:  Epigenetic
Novelty:  0.09769287
Score:  0.428
Data Source:  STRINGDB
HAUS3
Tbio
Novelty:  0.00398858
Score:  0.42
Data Source:  STRINGDB
ZDHHC7
Tbio
Family:  Enzyme
Novelty:  0.07453193
Score:  0.407
Data Source:  STRINGDB
PCDHB7
Tdark
Novelty:  0.60789936
Score:  0.404
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

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1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
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Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Sequence Alignment (ISA)
NTNU_SB
Non-traceable Author Statement (NAS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
7
4
10
96.4
total cholesterol measurement
2
2
2
82.3
apolipoprotein B measurement
1
1
1
68.5
kidney cancer
1
1
0
2.5
44.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
10
96.4
total cholesterol measurement
2
82.3
apolipoprotein B measurement
1
68.5
kidney cancer
0
2.5
44.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 135
100614698
Macaque
zinc finger protein 135
709957
Horse
zinc finger protein 135
VGNC:49296
100063880
Cow
zinc finger protein 135
VGNC:37209
508062
Pig
zinc finger protein 135
102159974
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 135
Macaque
zinc finger protein 135
Horse
zinc finger protein 135
Cow
zinc finger protein 135
Pig
zinc finger protein 135
Publication Statistics
PubMed Score 496.92
PubMed score by year
PubTator Score 1239.79
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title