Tdark ZNF121 Zinc finger protein 121

Protein Summary

Description

May be involved in transcriptional regulation.

Uniprot Accession IDs

• P58317

Gene Name

• ZNF121

Ensembl ID

• ENST00000320451
• ENSP00000326967
• ENSG00000197961
• ENST00000586602
• ENSP00000468643

Symbol

• ZNF20
• ZHC32
• ZNF20
• D19S204

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.61
histone modification site profile	0.54
tissue	0.52
interacting protein	0.49
cell line	0.45

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.5   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 42   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.5   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 42   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Expression Data (0 Tissues)

tutorial

No expression data found

Protein Sequence and Structure

Residue Counts

Protein Sequence

Find Targets by Sequence

Show Full Sequence

ProtVista Viewer

Related Tools (3)

GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

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GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

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ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

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Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (19)

Explore Interacting Targets

1 – 10 of 19

• See Interactions on String-DB

ZBTB48

Tbio

Family:  TF

Novelty:  0.07020518

p_int:  0.996954306

p_ni:  0.002892987

p_wrong:  0.000152707

Data Source:  BioPlex

ZNF324B

Tdark

Family:  TF

Novelty:  1.89922228

p_int:  0.995968534

p_ni:  0.004031456

p_wrong:  1e-8

Score:  0.159

Data Source:  BioPlex,STRINGDB

CDX1

Tbio

Family:  TF

Novelty:  0.00815821

p_int:  0.993971307

p_ni:  0.006028691

p_wrong:  2e-9

Score:  0.16

Data Source:  BioPlex,STRINGDB

ZKSCAN8

Tbio

Family:  TF

Novelty:  0.17881042

p_int:  0.990812343

p_ni:  0.00918586

p_wrong:  0.000001797

Data Source:  BioPlex

GNL3

Tbio

Novelty:  0.00886703

p_int:  0.98783298

p_ni:  0.012100622

p_wrong:  0.000066397

Data Source:  BioPlex

ZNF169

Tdark

Family:  TF

Novelty:  1.09432767

p_int:  0.982427394

p_ni:  0.01756859

p_wrong:  0.000004016

Data Source:  BioPlex

ZNF286A

Tdark

Family:  TF

Novelty:  3

p_int:  0.961391527

p_ni:  0.038608007

p_wrong:  4.66e-7

Data Source:  BioPlex

RPS14

Tbio

Novelty:  0.00576737

p_int:  0.943396757

p_ni:  0.056600867

p_wrong:  0.000002376

Data Source:  BioPlex

RPSA

Tbio

Novelty:  0.00250446

p_int:  0.936393497

p_ni:  0.063598327

p_wrong:  0.000008176

Score:  0.211

Data Source:  BioPlex,STRINGDB

ZNF2

Tbio

Family:  TF

Novelty:  0.01062543

p_int:  0.936393497

p_ni:  0.063598327

p_wrong:  0.000008176

Data Source:  BioPlex

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (4)

Functions (3)

Components (1)

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1 – 3 of 3

GO Term	Evidence	Assigned by
DNA-binding transcription factor activity, RNA polymerase II-specific	Inferred from Sequence Alignment (ISA)	NTNU_SB
DNA binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW
metal ion binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW

Disease Associations (null)

No disease associations found

GWAS Traits (0)

No GWAS traits found

Find similar targets by:

UniProt Keyword Find Similar Targets

No Header	No Header
Complete proteome
DNA-binding
Metal-binding
Nucleus
Reference proteome
Repeat
Transcription
Transcription regulation
Zinc
Zinc-finger

IDG Resources

No IDG generated resources found

Orthologs (2)

1 – 2 of 2

Species	Name	Source ID	Gene ID	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 121	VGNC:11476	455683
Macaque	zinc finger protein 121		715010

Species	Name	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 121
Macaque	zinc finger protein 121

Publication Statistics

PubMed Score 4.50

PubMed score by year

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PubTator Score 0.62

PubTator score by year

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Related Publications

Text Mined References (6)

GeneRif Annotations (2)

Items per page:

10

0 of 0

PMID	Year	Title