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Tdark
ZMYM6
Zinc finger MYM-type protein 6

Protein Summary
Description
Plays a role in the regulation of cell morphology and cytoskeletal organization.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000317538
  • ENSP00000326695
  • ENSG00000163867
  • ENST00000357182
  • ENSP00000349708
  • ENST00000373333
  • ENSP00000362430

Symbol
  • Buster2
  • KIAA1353
  • ZNF258
  • MYM
  • ZBED7
  • ZNF258
  • Buster2
  • ZNF198L4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.71
cell line
0.68
transcription factor perturbation
0.68
transcription factor binding site profile
0.64
histone modification site profile
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.85   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.85   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (62)
CRTAC1
Tbio
Novelty:  0.09442374
p_int:  0.999958043
p_ni:  0.000041957
Data Source:  BioPlex
PTS
Tbio
Family:  Enzyme
Novelty:  0.00279396
p_int:  0.999882792
p_ni:  0.000117208
Data Source:  BioPlex
CRYAA
Tchem
Novelty:  0.01914081
p_int:  0.99982405
p_ni:  0.000175901
p_wrong:  5e-8
Data Source:  BioPlex
ENTHD1
Tdark
Novelty:  5.29427978
p_int:  0.999757793
p_ni:  0.000242207
Data Source:  BioPlex
GRB2
Tchem
Novelty:  0.00091605
p_int:  0.999686578
p_ni:  0.000313419
p_wrong:  3e-9
Data Source:  BioPlex
LSP1
Tbio
Novelty:  0.00889927
p_int:  0.99944983
p_ni:  0.00055017
Data Source:  BioPlex
CTDSP2
Tbio
Family:  Enzyme
Novelty:  0.01033594
p_int:  0.998475704
p_ni:  0.001524296
Data Source:  BioPlex
PAGE1
Tbio
Novelty:  0.02731969
p_int:  0.998418146
p_ni:  0.00158185
p_wrong:  4e-9
Data Source:  BioPlex
ISCA2
Tbio
Novelty:  0.02194373
p_int:  0.998203732
p_ni:  0.001796264
p_wrong:  5e-9
Data Source:  BioPlex
TUFM
Tchem
Novelty:  0.03251632
p_int:  0.997946499
p_ni:  0.002053501
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cigarettes per day measurement
1
1
1
6.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cigarettes per day measurement
1
6.7
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger MYM-type containing 6
VGNC:10872
744232
Mouse
MGI:106505
100177
Rat
RGD:1561833
362602
Dog
zinc finger MYM-type containing 6
VGNC:48649
475341
Horse
zinc finger MYM-type containing 6
VGNC:25254
100629888
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger MYM-type containing 6
Mouse
Rat
Dog
zinc finger MYM-type containing 6
Horse
zinc finger MYM-type containing 6
Publication Statistics
PubMed Score 1.85
PubMed score by year
PubTator Score 0.89
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title