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Tbio
ZMYM2
Zinc finger MYM-type protein 2

Protein Summary
Description
May function as a transcription factor. The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000382871
  • ENSP00000372324
  • ENSG00000121741
  • ENST00000382874
  • ENSP00000372327
  • ENST00000610343
  • ENSP00000479904

Symbol
  • FIM
  • RAMP
  • ZNF198
  • FIM
  • MYM
  • RAMP
  • SCLL
  • ZNF198
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
virus perturbation
0.9
microRNA
0.81
transcription factor
0.76
transcription factor binding site profile
0.76


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.95   (req: < 5)
Gene RIFs: 22   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.95   (req: >= 5)
Gene RIFs: 22   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0