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Tbio
ZIM2
Zinc finger imprinted 2

Protein Summary
Description
May be involved in transcriptional regulation. In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. [provided by RefSeq, Oct 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000593711
  • ENSP00000472306
  • ENSG00000269699
  • ENST00000599935
  • ENSP00000468984
  • ENST00000601070
  • ENSP00000470326
  • ENST00000629319
  • ENSP00000486502

Symbol
  • ZNF656
  • ZNF656
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.79
cell line
0.62
protein domain
0.58
PubMedID
0.58
cell type or tissue
0.51


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.53   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 137   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.53   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 137   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
TRIM39
Tbio
Family:  Enzyme
Novelty:  0.0837441
p_int:  0.999796593
p_ni:  0.000203407
Score:  0.207
Data Source:  BioPlex,STRINGDB
SAV1
Tbio
Novelty:  0.00962335
p_int:  0.998928438
p_ni:  0.001071558
p_wrong:  4e-9
Score:  0.54
Data Source:  BioPlex,STRINGDB
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.992855361
p_ni:  0.007144639
Score:  0.926
Data Source:  BioPlex,STRINGDB
TRIM24
Tchem
Family:  Epigenetic
Novelty:  0.00532747
p_int:  0.988846436
p_ni:  0.011153564
Score:  0.201
Data Source:  BioPlex,STRINGDB
STK3
Tchem
Family:  Kinase
Novelty:  0.0529257
p_int:  0.972238178
p_ni:  0.027761822
Score:  0.613
Data Source:  BioPlex,STRINGDB
APPBP2
Tbio
Novelty:  0.14742368
p_int:  0.939325256
p_ni:  0.060672092
p_wrong:  0.000002652
Score:  0.23
Data Source:  BioPlex,STRINGDB
TRIM33
Tchem
Family:  Epigenetic
Novelty:  0.00415877
p_int:  0.852945116
p_ni:  0.147054884
Score:  0.22
Data Source:  BioPlex,STRINGDB
ZCWPW1
Tbio
Family:  Epigenetic
Novelty:  0.11264543
p_int:  0.846264946
p_ni:  0.000146962
p_wrong:  0.153588092
Score:  0.54
Data Source:  BioPlex,STRINGDB
GOT1
Tbio
Family:  Enzyme
Novelty:  0.00448817
Score:  0.8
Data Source:  STRINGDB
USP29
Tbio
Family:  Enzyme
Novelty:  0.04574437
Score:  0.712
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

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Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Cow
zinc finger imprinted 2
VGNC:52291
444865
Species
Name
OMA
EggNOG
Inparanoid
Cow
zinc finger imprinted 2
Publication Statistics
PubMed Score 11.53
PubMed score by year
PubTator Score 3.07
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title