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Tdark
ZFP41
Zinc finger protein 41 homolog

Protein Summary
Description
A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000626353
  • ENSP00000486248
  • ENSG00000181638
  • ENST00000627729
  • ENSP00000486020

Symbol
  • ZNF753
  • zfp-41
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.89
tissue sample
0.66
transcription factor
0.63
tissue
0.56
transcription factor binding site profile
0.56


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.51   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.51   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
FBN1
Tbio
Novelty:  0.00074957
p_int:  0.999998636
p_ni:  0.000001148
p_wrong:  2.17e-7
Data Source:  BioPlex
ZC3H4
Tbio
Novelty:  0.14897433
p_int:  0.999997633
p_ni:  0.000002367
p_wrong:  1e-9
Data Source:  BioPlex
LRP4
Tbio
Novelty:  0.01336125
p_int:  0.999995577
p_ni:  0.000004422
p_wrong:  2e-9
Data Source:  BioPlex
LRP1B
Tbio
Novelty:  0.01443405
p_int:  0.99999363
p_ni:  0.000006369
Data Source:  BioPlex
SORL1
Tbio
Novelty:  0.00380895
p_int:  0.999983262
p_ni:  0.000016738
Data Source:  BioPlex
MPRIP
Tbio
Family:  Enzyme
Novelty:  0.03253403
p_int:  0.999976137
p_ni:  0.000023855
p_wrong:  7e-9
Data Source:  BioPlex
FBLN1
Tbio
Novelty:  0.00796703
p_int:  0.999965675
p_ni:  0.000034325
Data Source:  BioPlex
LDLR
Tchem
Novelty:  0.06585434
p_int:  0.999947934
p_ni:  0.000052044
p_wrong:  2.1e-8
Data Source:  BioPlex
PPP1R10
Tbio
Family:  Enzyme
Novelty:  0.01119155
p_int:  0.999876092
p_ni:  0.000123736
p_wrong:  1.72e-7
Data Source:  BioPlex
PYGB
Tchem
Family:  Enzyme
Novelty:  0.00224148
p_int:  0.999830621
p_ni:  0.000169379
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
6
5
7
96.4
apolipoprotein A 1 measurement
2
3
3
92.9
body height
1
1
1
64.9
BMI-adjusted hip circumference
1
3
3
45.2
mathematical ability
2
1
2
30.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
7
96.4
apolipoprotein A 1 measurement
3
92.9
body height
1
64.9
BMI-adjusted hip circumference
3
45.2
mathematical ability
2
30.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ZFP41 zinc finger protein
472882
Mouse
MGI:99186
22701
Rat
RGD:1307587
100910508
Dog
ZFP41 zinc finger protein
102152064
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ZFP41 zinc finger protein
Mouse
Rat
Dog
ZFP41 zinc finger protein
Publication Statistics
PubMed Score 0.51
PubMed score by year
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Related Publications
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PMID
Year
Title