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Tbio
ZFP37
Zinc finger protein 37 homolog

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a transcription factor that belongs to a large family of zinc finger proteins. A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374227
  • ENSP00000363344
  • ENSG00000136866
  • ENST00000553380
  • ENSP00000452552
  • ENST00000555206
  • ENSP00000451310

Symbol
  • ZNF906
  • zfp-37
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
protein domain
0.58
tissue
0.52
transcription factor binding site profile
0.5
virus perturbation
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.57   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 67   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.57   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 67   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
WDR46
Tbio
Novelty:  0.19307408
p_int:  0.995999898
p_ni:  0.000003146
p_wrong:  0.003996956
Score:  0.189
Data Source:  BioPlex,STRINGDB
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.903
Data Source:  STRINGDB
SLC46A2
Tdark
Family:  Transporter
Novelty:  0.12003352
Score:  0.754
Data Source:  STRINGDB
FHIT
Tchem
Family:  Enzyme
Novelty:  0.0012803
Score:  0.712
Data Source:  STRINGDB
COP1
Tbio
Family:  Enzyme
Novelty:  0.10908534
Score:  0.688
Data Source:  STRINGDB
FKBP15
Tbio
Novelty:  0.0570695
Score:  0.669
Data Source:  STRINGDB
BRINP2
Tdark
Novelty:  0.5101917
Score:  0.654
Data Source:  STRINGDB
TAF11
Tchem
Novelty:  0.10299251
Score:  0.644
Data Source:  STRINGDB
SF3B4
Tbio
Novelty:  0.0197008
Score:  0.643
Data Source:  STRINGDB
TMEM62
Tdark
Novelty:  1.79070108
Score:  0.627
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

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Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
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Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Sequence Alignment (ISA)
NTNU_SB
Non-traceable Author Statement (NAS)
UniProtKB
Non-traceable Author Statement (NAS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
1
1
82.6
mean reticulocyte volume
1
1
1
80.4
mean corpuscular hemoglobin concentration
1
1
1
71.9
neutrophil count
1
1
1
59
reticulocyte count
1
1
1
46.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
82.6
mean reticulocyte volume
1
80.4
mean corpuscular hemoglobin concentration
1
71.9
neutrophil count
1
59
reticulocyte count
1
46.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ZFP37 zinc finger protein
VGNC:8953
473025
Macaque
ZFP37 zinc finger protein
710438
Mouse
MGI:99181
22696
Rat
Dog
ZFP37 zinc finger protein
VGNC:49667
111089991
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ZFP37 zinc finger protein
Macaque
ZFP37 zinc finger protein
Mouse
Rat
Dog
ZFP37 zinc finger protein
Publication Statistics
PubMed Score 8.57
PubMed score by year
PubTator Score 2.19
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title