You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
ZFP1
Zinc finger protein 1 homolog

Protein Summary
Description
May be involved in transcriptional regulation. This gene belongs to the zinc finger protein family. Some members of this family bind to DNA by zinc-mediated secondary structures called zinc fingers, and are involved in transcriptional regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000393430
  • ENSP00000377080
  • ENSG00000184517
  • ENST00000570010
  • ENSP00000457044
  • ENST00000642425
  • ENSP00000496743
  • ENSG00000285178
  • ENST00000642672
  • ENSP00000496712

Symbol
  • ZNF475
  • ZNF475
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.86
transcription factor binding site profile
0.81
virus perturbation
0.72
protein domain
0.58
microRNA
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.11   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.11   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
AKR1C2
Tchem
Family:  Enzyme
Novelty:  0.00134228
p_int:  0.999999654
p_ni:  3.44e-7
p_wrong:  2e-9
Score:  0.329
Data Source:  BioPlex,STRINGDB
SERTAD4
Tdark
Novelty:  0.70786986
p_int:  0.999995438
p_ni:  0.00000451
p_wrong:  5.2e-8
Score:  0.234
Data Source:  BioPlex,STRINGDB
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.999740333
p_ni:  0.000033115
p_wrong:  0.000226552
Score:  0.918
Data Source:  BioPlex,STRINGDB
WASHC3
Tdark
Novelty:  0.18307321
p_int:  0.999734253
p_ni:  0.00003975
p_wrong:  0.000225998
Data Source:  BioPlex
SESN3
Tbio
Novelty:  0.03768678
p_int:  0.999603725
p_ni:  0.000195011
p_wrong:  0.000201264
Score:  0.461
Data Source:  BioPlex,STRINGDB
CASZ1
Tbio
Novelty:  0.01343868
Score:  0.907
Data Source:  STRINGDB
CIZ1
Tbio
Novelty:  0.03730538
Score:  0.568
Data Source:  STRINGDB
KLHDC10
Tdark
Novelty:  0.40978227
Score:  0.549
Data Source:  STRINGDB
GATM
Tbio
Family:  Enzyme
Novelty:  0.00340356
Score:  0.518
Data Source:  STRINGDB
DOT1L
Tchem
Family:  Epigenetic
Novelty:  0.00361358
Score:  0.511
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (34)
Items per page:
1 – 5 of 34
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
6
5
3
1.2
96.1
6
5
3
1.2
96.1
3
3
1
1.3
84
3
3
1
1.3
84
lymphocyte count
2
2
2
77.8
Items per page:
1 – 5 of 34
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
1.2
96.1
3
1.2
96.1
1
1.3
84
1
1.3
84
lymphocyte count
2
77.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ZFP1 zinc finger protein
VGNC:9206
468028
Macaque
ZFP1 zinc finger protein
713648
Mouse
MGI:99154
22640
Rat
RGD:1565049
498952
Dog
ZFP1 zinc finger protein
VGNC:48609
100687945
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ZFP1 zinc finger protein
Macaque
ZFP1 zinc finger protein
Mouse
Rat
Dog
ZFP1 zinc finger protein
Publication Statistics
PubMed Score 26.11
PubMed score by year
PubTator Score 0.75
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title