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Tbio
ZDHHC9
Palmitoyltransferase ZDHHC9

Protein Summary
Description
The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS. This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357166
  • ENSP00000349689
  • ENSG00000188706
  • ENST00000371064
  • ENSP00000360103

Symbol
  • CXorf11
  • ZDHHC10
  • ZNF379
  • ZNF380
  • CGI89
  • DHHC9
  • MMSA1
  • MRXSZ
  • ZNF379
  • ZNF380
  • CXorf11
  • ZDHHC10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.8
tissue
0.68
cellular component
0.67
microRNA
0.66
small molecule perturbation
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.62   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 189   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.62   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 189   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0