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Tbio
ZDHHC13
Palmitoyltransferase ZDHHC13

Protein Summary
Description
Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000399351
  • ENSP00000382288
  • ENSG00000177054
  • ENST00000446113
  • ENSP00000400113

Symbol
  • HIP14L
  • HIP3RP
  • HIP14L
  • HIP3RP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.88
histone modification site profile
0.75
phenotype
0.71
cellular component
0.64
tissue sample
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.85   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 156   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.85   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 156   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (58)
PLAC8L1
Tdark
Novelty:  2.10744169
p_int:  0.999911822
p_ni:  0.000088178
Score:  0.672
Data Source:  BioPlex,STRINGDB
ARSE
Tbio
Family:  Enzyme
Novelty:  0.00151862
p_int:  0.998702505
p_ni:  0.001297495
Data Source:  BioPlex
WBP1
Tbio
Novelty:  1.24967974
p_int:  0.975346633
p_ni:  0.024653367
Score:  0.184
Data Source:  BioPlex,STRINGDB
TACR3
Tchem
Family:  GPCR
Novelty:  0.00351352
p_int:  0.963891679
p_ni:  0.036108321
Data Source:  BioPlex
C3AR1
Tchem
Family:  GPCR
Novelty:  0.00527301
p_int:  0.951709224
p_ni:  0.048290776
Data Source:  BioPlex
CCR6
Tchem
Family:  GPCR
Novelty:  0.00257933
p_int:  0.886945844
p_ni:  0.113054155
p_wrong:  1e-9
Data Source:  BioPlex
MRAP2
Tbio
Novelty:  0.0420503
p_int:  0.850454317
p_ni:  0.149545623
p_wrong:  5.9e-8
Data Source:  BioPlex
CD83
Tbio
Novelty:  0.00138653
p_int:  0.844432163
p_ni:  0.155565276
p_wrong:  0.000002561
Data Source:  BioPlex
SPINT2
Tbio
Family:  Enzyme
Novelty:  0.0046602
p_int:  0.814698921
p_ni:  0.185301079
Data Source:  BioPlex
IPPK
Tbio
Family:  Enzyme
Novelty:  0.02169701
p_int:  0.808799546
p_ni:  0.191200406
p_wrong:  4.7e-8
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
2
4
4
91.9
mean reticulocyte volume
1
3
3
90.8
mean corpuscular hemoglobin concentration
1
1
1
85.2
red blood cell density measurement
1
1
1
83.3
erythrocyte count
1
1
1
65.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
4
91.9
mean reticulocyte volume
3
90.8
mean corpuscular hemoglobin concentration
1
85.2
red blood cell density measurement
1
83.3
erythrocyte count
1
65.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (16)
1 – 5 of 16
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger DHHC-type containing 13
VGNC:7677
451071
Macaque
zinc finger DHHC-type containing 13
702589
Mouse
MGI:1919227
243983
Rat
RGD:1309736
365252
Dog
zinc finger DHHC-type containing 13
VGNC:48579
613004
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger DHHC-type containing 13
Macaque
zinc finger DHHC-type containing 13
Mouse
Rat
Dog
zinc finger DHHC-type containing 13
Publication Statistics
PubMed Score 7.85
PubMed score by year
PubTator Score 1.23
PubTator score by year
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Related Publications
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PMID
Year
Title