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Tdark
ZDHHC12
Probable palmitoyltransferase ZDHHC12

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372663
  • ENSP00000361748
  • ENSG00000160446

Symbol
  • ZNF400
  • ZNF400
  • DHHC-12
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
tissue sample
0.59
transcription factor binding site profile
0.58
transcription factor perturbation
0.54
molecular function
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.57   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 58   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.57   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (10)
ZNF454
Tdark
Family:  TF
Novelty:  1.48640477
Score:  0.498
Data Source:  STRINGDB
GPHN
Tbio
Novelty:  0.0020752
Score:  0.481
Data Source:  STRINGDB
TMEM179
Tdark
Novelty:  2.21288966
Score:  0.478
Data Source:  STRINGDB
ZNF540
Tbio
Family:  TF
Novelty:  0.42941109
Score:  0.478
Data Source:  STRINGDB
TMEM134
Tdark
Novelty:  0.42629221
Score:  0.473
Data Source:  STRINGDB
KIAA1551
Tdark
Novelty:  0.25602289
Score:  0.471
Data Source:  STRINGDB
NRIP2
Tdark
Novelty:  0.5598619
Score:  0.467
Data Source:  STRINGDB
ZNF419
Tdark
Family:  TF
Novelty:  0.69013025
Score:  0.456
Data Source:  STRINGDB
SERINC2
Tbio
Novelty:  0.13677995
Score:  0.445
Data Source:  STRINGDB
REEP6
Tbio
Novelty:  0.10645981
Score:  0.409
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (20)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
5
3
5
93.9
sex hormone-binding globulin measurement
8
1
7
7.4
84.3
low density lipoprotein cholesterol measurement
4
3
4
79.9
platelet crit
2
2
2
79.8
platelet count
2
2
2
74
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
5
93.9
sex hormone-binding globulin measurement
7
7.4
84.3
low density lipoprotein cholesterol measurement
4
79.9
platelet crit
2
79.8
platelet count
2
74
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger DHHC-type containing 12
VGNC:8952
464774
Macaque
zinc finger DHHC-type containing 12
722606
Mouse
MGI:1913470
66220
Rat
RGD:1306593
366014
Dog
zinc finger DHHC-type containing 12
VGNC:48578
608478
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger DHHC-type containing 12
Macaque
zinc finger DHHC-type containing 12
Mouse
Rat
Dog
zinc finger DHHC-type containing 12
Publication Statistics
PubMed Score 3.57
PubMed score by year
PubTator Score 0.83
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title