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Tbio
ZDHHC11
Probable palmitoyltransferase ZDHHC11

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000283441
  • ENSP00000283441
  • ENSG00000188818
  • ENST00000511539
  • ENSP00000427067

Symbol
  • ZNF399
  • ZNF399
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
0.59
cellular component
0.56
cell line
0.55
tissue sample
0.55
molecular function
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.69   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 38   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.69   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 38   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
RETREG2
Tdark
Novelty:  0.18851807
p_int:  0.999659126
p_ni:  0.000234098
p_wrong:  0.000106776
Score:  0.188
Data Source:  BioPlex,STRINGDB
LNPK
Tbio
Novelty:  0.07736762
p_int:  0.996982564
p_ni:  0.003017436
Data Source:  BioPlex
MAPK3
Tchem
Family:  Kinase
Novelty:  0.00012969
p_int:  0.986668658
p_ni:  0.013331342
Score:  0.206
Data Source:  BioPlex,STRINGDB
FAM241A
Tdark
Novelty:  1.04041354
p_int:  0.986532629
p_ni:  0.013387447
p_wrong:  0.000079924
Data Source:  BioPlex
APOB
Tchem
Novelty:  0.00008247
p_int:  0.956770367
p_ni:  0.043229632
Score:  0.177
Data Source:  BioPlex,STRINGDB
EFNB1
Tbio
Novelty:  0.00523161
p_int:  0.951860396
p_ni:  0.048139457
p_wrong:  1.47e-7
Score:  0.185
Data Source:  BioPlex,STRINGDB
FGFR1
Tclin
Family:  Kinase
Novelty:  0.00055714
p_int:  0.919195182
p_ni:  0.078284552
p_wrong:  0.002520266
Data Source:  BioPlex
PPM1A
Tchem
Family:  Enzyme
Novelty:  0.01464968
p_int:  0.862929718
p_ni:  0.136481977
p_wrong:  0.000588305
Score:  0.159
Data Source:  BioPlex,STRINGDB
GLMN
Tbio
Novelty:  0.01940401
p_int:  0.845779541
p_ni:  0.154220459
Data Source:  BioPlex
ANKRD13A
Tbio
Novelty:  0.61940334
p_int:  0.752623216
p_ni:  0.247376784
Score:  0.167
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
1
1
1
22.8
BMI-adjusted waist circumference
1
1
1
18.4
blood urea nitrogen measurement
1
1
1
6.8
serum urea measurement
1
1
1
6
hemoglobin measurement
1
1
1
5.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
1
22.8
BMI-adjusted waist circumference
1
18.4
blood urea nitrogen measurement
1
6.8
serum urea measurement
1
6
hemoglobin measurement
1
5.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 5.69
PubMed score by year
PubTator Score 1.42
PubTator score by year
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Related Publications
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PMID
Year
Title