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Tbio
ZCWPW1
Zinc finger CW-type PWWP domain protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360951
  • ENSP00000354210
  • ENSG00000078487
  • ENST00000398027
  • ENSP00000381109
  • ENST00000490721
  • ENSP00000419187

Symbol
  • ZCW1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.96
transcription factor
0.8
small molecule perturbation
0.63
PubMedID
0.58
tissue sample
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.7   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 64   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.7   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (73)
ZIM2
Tbio
Family:  TF
Novelty:  0.08135678
p_int:  0.846264946
p_ni:  0.000146962
p_wrong:  0.153588092
Score:  0.54
Data Source:  BioPlex,STRINGDB
NME8
Tbio
Novelty:  0.05439119
Score:  0.823
Data Source:  STRINGDB
CASS4
Tbio
Novelty:  0.01000437
Score:  0.8
Data Source:  STRINGDB
RIN3
Tbio
Novelty:  0.07790793
Score:  0.739
Data Source:  STRINGDB
FERMT2
Tbio
Novelty:  0.01020276
Score:  0.736
Data Source:  STRINGDB
SLC24A4
Tbio
Family:  Transporter
Novelty:  0.02745216
Score:  0.734
Data Source:  STRINGDB
ABCA7
Tbio
Family:  Transporter
Novelty:  0.00808369
Score:  0.731
Data Source:  STRINGDB
MS4A6A
Tbio
Novelty:  0.04742307
Score:  0.709
Data Source:  STRINGDB
CELF1
Tbio
Novelty:  0.00666261
Score:  0.706
Data Source:  STRINGDB
SORL1
Tbio
Novelty:  0.00380895
Score:  0.704
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (31)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
2
1
4
92.3
family history of Alzheimer’s disease
2
3
0
4.3
91.7
Alzheimer disease
3
2
0
6.7
91.4
hemoglobin measurement
2
3
3
85.5
educational attainment
1
3
3
82
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
4
92.3
family history of Alzheimer’s disease
0
4.3
91.7
Alzheimer disease
0
6.7
91.4
hemoglobin measurement
3
85.5
educational attainment
3
82
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger CW-type and PWWP domain containing 1
VGNC:4569
738925
Macaque
zinc finger CW-type and PWWP domain containing 1
711911
Mouse
MGI:2685899
381678
Rat
RGD:6497217
100910636
Dog
zinc finger CW-type and PWWP domain containing 1
VGNC:48575
489840
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger CW-type and PWWP domain containing 1
Macaque
zinc finger CW-type and PWWP domain containing 1
Mouse
Rat
Dog
zinc finger CW-type and PWWP domain containing 1
Publication Statistics
PubMed Score 10.70
PubMed score by year
PubTator Score 7.66
PubTator score by year
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Related Publications
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PMID
Year
Title