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Tbio
ZC3H14
Zinc finger CCCH domain-containing protein 14

Protein Summary
Description
Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides. The protein encoded by this gene is a poly(A)-binding protein that can affect gene expression and poly(A) tail length. The encoded protein may influence mRNA stability, nuclear export, and translation. [provided by RefSeq, May 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000251038
  • ENSP00000251038
  • ENSG00000100722
  • ENST00000302216
  • ENSP00000307025
  • ENST00000318308
  • ENSP00000327176
  • ENST00000336693
  • ENSP00000338002
  • ENST00000393514
  • ENSP00000377150
  • ENST00000406216
  • ENSP00000384682
  • ENST00000555755
  • ENSP00000452475

Symbol
  • SUT2
  • MRT56
  • UKp68
  • MSUT-2
  • NY-REN-37
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.93
transcription factor perturbation
0.88
ligand (protein) perturbation
0.83
tissue
0.73
transcription factor
0.73


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.35   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 133   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.35   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 133   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (142)
NKAPD1
Tdark
Novelty:  1.56979675
p_int:  0.999996652
p_ni:  0.000003348
Data Source:  BioPlex
PNN
Tbio
Novelty:  0.01395394
p_int:  0.999984909
p_ni:  0.000015091
Score:  0.558
Data Source:  BioPlex,STRINGDB
CCDC9
Tdark
Novelty:  0.73149492
p_int:  0.999800645
p_ni:  0.000199339
p_wrong:  1.7e-8
Data Source:  BioPlex
SNIP1
Tbio
Novelty:  0.01865867
p_int:  0.999637461
p_ni:  0.000362539
Score:  0.37
Data Source:  BioPlex,STRINGDB
SARNP
Tbio
Novelty:  0.00987312
p_int:  0.999543448
p_ni:  0.000456552
Score:  0.229
Data Source:  BioPlex,STRINGDB
SAP18
Tbio
Family:  Enzyme
Novelty:  0.03918373
p_int:  0.998881289
p_ni:  0.001118695
p_wrong:  1.6e-8
Data Source:  BioPlex
LUC7L2
Tdark
Novelty:  0.36989457
p_int:  0.998685685
p_ni:  0.001314315
Score:  0.183
Data Source:  BioPlex,STRINGDB
WSB2
Tbio
Novelty:  0.03939755
p_int:  0.998318342
p_ni:  0.001681658
Score:  0.67
Data Source:  BioPlex,STRINGDB
ZC3H18
Tdark
Novelty:  0.3515546
p_int:  0.996585174
p_ni:  0.003414826
Score:  0.241
Data Source:  BioPlex,STRINGDB
CHTOP
Tbio
Novelty:  0.04170391
p_int:  0.992370739
p_ni:  0.007629242
p_wrong:  2e-8
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (12)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
1
1
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
1
17.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCCH-type containing 14
VGNC:7636
453092
Macaque
zinc finger CCCH-type containing 14
694233
Mouse
MGI:1919824
75553
Rat
RGD:621850
192359
Dog
zinc finger CCCH-type containing 14
VGNC:48555
480412
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCCH-type containing 14
Macaque
zinc finger CCCH-type containing 14
Mouse
Rat
Dog
zinc finger CCCH-type containing 14
Publication Statistics
PubMed Score 20.35
PubMed score by year
PubTator Score 8.70
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title