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Tbio
ZC3H11A
Zinc finger CCCH domain-containing protein 11A

Protein Summary
Description
Involved in nuclear mRNA export; probably mediated by association with the TREX complex.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000332127
  • ENSP00000333253
  • ENSG00000058673
  • ENST00000367210
  • ENSP00000356179
  • ENST00000367212
  • ENSP00000356181
  • ENST00000367214
  • ENSP00000356183
  • ENST00000639812
  • ENSP00000491830

Symbol
  • KIAA0663
  • ZC3HDC11A
  • ZC3HDC11A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.98
virus perturbation
0.98
transcription factor binding site profile
0.82
kinase perturbation
0.76
microRNA
0.76


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.87   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 130   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.87   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 130   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (152)
SARNP
Tbio
Novelty:  0.00987312
p_int:  0.999982022
p_ni:  0.000017978
Score:  0.955
Data Source:  BioPlex,STRINGDB
ELAVL2
Tbio
Novelty:  0.00370708
p_int:  0.999518257
p_ni:  0.000481743
Data Source:  BioPlex
SPANXC
Tbio
Novelty:  0.14907666
p_int:  0.998530344
p_ni:  0.001469655
p_wrong:  1e-9
Data Source:  BioPlex
LARP4B
Tbio
Novelty:  0.11363794
p_int:  0.994037046
p_ni:  0.005962762
p_wrong:  1.92e-7
Data Source:  BioPlex
NKAPD1
Tdark
Novelty:  1.56979675
p_int:  0.992208075
p_ni:  0.007791924
Data Source:  BioPlex
KBTBD7
Tbio
Novelty:  0.4947466
p_int:  0.966077077
p_ni:  0.033904324
p_wrong:  0.000018599
Data Source:  BioPlex
APOBEC3D
Tbio
Novelty:  0.01102619
p_int:  0.952383585
p_ni:  0.047616415
Data Source:  BioPlex
ZC3H18
Tdark
Novelty:  0.3515546
p_int:  0.936410935
p_ni:  0.063589065
Score:  0.227
Data Source:  BioPlex,STRINGDB
GSPT2
Tchem
Family:  Enzyme
Novelty:  0.08140512
p_int:  0.925568278
p_ni:  0.074404435
p_wrong:  0.000027287
Score:  0.532
Data Source:  BioPlex,STRINGDB
XAGE1A
Tbio
Novelty:  0.04421526
p_int:  0.857857202
p_ni:  0.142142798
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (8)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Metabolism of RNA
Reactome
Processing of Capped Intron-Containing Pre-mRNA
Reactome
RNA Polymerase II Transcription
Reactome
RNA Polymerase II Transcription Termination
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Metabolism of RNA
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
RNA Polymerase II Transcription Termination
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
1
1
1
85.5
1
2
2
81.8
hemoglobin measurement
1
1
1
69.4
lymphocyte count
2
1
2
69
appendicular lean mass
1
1
1
53.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
1
85.5
2
81.8
hemoglobin measurement
1
69.4
lymphocyte count
2
69
appendicular lean mass
1
53.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCCH-type containing 11A
VGNC:8128
462805
Macaque
zinc finger CCCH-type containing 11A
701537
Mouse
MGI:1917829
70579
Rat
RGD:1308290
360845
Dog
zinc finger CCCH-type containing 11A
478932
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCCH-type containing 11A
Macaque
zinc finger CCCH-type containing 11A
Mouse
Rat
Dog
zinc finger CCCH-type containing 11A
Publication Statistics
PubMed Score 3.87
PubMed score by year
PubTator Score 2.69
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title