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Tdark
ZC2HC1A
Zinc finger C2HC domain-containing protein 1A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263849
  • ENSP00000263849
  • ENSG00000104427

Symbol
  • C8orf70
  • FAM164A
  • CGI-62
  • C8orf70
  • FAM164A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.87
microRNA
0.66
cell type or tissue
0.58
tissue sample
0.57
cell line
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.99   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 245   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.99   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 245   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
DGKG
Tbio
Family:  Enzyme
Novelty:  0.03666646
p_int:  1
Data Source:  BioPlex
CASTOR1
Tbio
Novelty:  0.10145237
p_int:  0.999999999
p_ni:  1e-9
Score:  0.877
Data Source:  BioPlex,STRINGDB
CAPS
Tbio
Novelty:  0.04549022
p_int:  0.999998631
p_ni:  1.84e-7
p_wrong:  0.000001185
Data Source:  BioPlex
WDR59
Tdark
Novelty:  0.22243351
Score:  0.737
Data Source:  STRINGDB
MIOS
Tdark
Novelty:  0.04252507
Score:  0.731
Data Source:  STRINGDB
RUFY3
Tbio
Novelty:  0.1517817
Score:  0.722
Data Source:  STRINGDB
WDR24
Tdark
Novelty:  0.48411996
Score:  0.705
Data Source:  STRINGDB
EEF1AKMT3
Tdark
Family:  Enzyme
Novelty:  0.24761808
Score:  0.63
Data Source:  STRINGDB
WBP4
Tbio
Novelty:  0.10095907
Score:  0.596
Data Source:  STRINGDB
CASTOR2
Tbio
Novelty:  0.3255398
Score:  0.574
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
4
4
5
98.4
lymphocyte percentage of leukocytes
2
2
2
93.9
neutrophil percentage of leukocytes
2
2
2
91.8
monocyte percentage of leukocytes
1
1
1
52
1
1
0
1.1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
5
98.4
lymphocyte percentage of leukocytes
2
93.9
neutrophil percentage of leukocytes
2
91.8
monocyte percentage of leukocytes
1
52
0
1.1
24.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger C2HC-type containing 1A
VGNC:7605
464243
Macaque
zinc finger C2HC-type containing 1A
698760
Mouse
MGI:1914556
67306
Rat
RGD:1311970
310244
Dog
zinc finger C2HC-type containing 1A
VGNC:48547
487009
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger C2HC-type containing 1A
Macaque
zinc finger C2HC-type containing 1A
Mouse
Rat
Dog
zinc finger C2HC-type containing 1A
Publication Statistics
PubMed Score 0.99
PubMed score by year
PubTator Score 0.95
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title