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Tbio
ZBTB5
Zinc finger and BTB domain-containing protein 5

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000307750
  • ENSP00000307604
  • ENSG00000168795

Symbol
  • KIAA0354
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.91
protein domain
0.85
transcription factor binding site profile
0.81
histone modification site profile
0.71
transcription factor
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.35   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 135   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.35   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 135   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (32)
GOPC
Tbio
Novelty:  0.01110168
p_int:  0.999999927
p_ni:  7e-8
p_wrong:  3e-9
Score:  0.15
Data Source:  BioPlex,STRINGDB
NPRL2
Tbio
Family:  Enzyme
Novelty:  0.02848752
p_int:  0.999998959
p_ni:  0.00000104
Score:  0.214
Data Source:  BioPlex,STRINGDB
KLHL40
Tbio
Novelty:  0.0432945
p_int:  0.999788979
p_ni:  0.000210907
p_wrong:  1.14e-7
Score:  0.196
Data Source:  BioPlex,STRINGDB
ZNF784
Tdark
Family:  TF
Novelty:  17.08860759
p_int:  0.999379776
p_ni:  0.000346621
p_wrong:  0.000273603
Data Source:  BioPlex
CDC16
Tbio
Novelty:  0.00916715
p_int:  0.997202636
p_ni:  0.002796595
p_wrong:  7.69e-7
Score:  0.15
Data Source:  BioPlex,STRINGDB
SEC13
Tbio
Novelty:  0.00709413
p_int:  0.996021535
p_ni:  0.003978456
p_wrong:  8e-9
Score:  0.183
Data Source:  BioPlex,STRINGDB
PDZK1P1
Tdark
p_int:  0.995338902
p_ni:  0.000365499
p_wrong:  0.004295599
Data Source:  BioPlex
SAAL1
Tdark
Novelty:  0.33089811
Score:  0.686
Data Source:  STRINGDB
ACTRT2
Tdark
Novelty:  0.38919779
Score:  0.602
Data Source:  STRINGDB
OR4D10
Tdark
Family:  oGPCR
Novelty:  3.91706296
Score:  0.594
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (7)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
1
1
1
67.1
daytime rest measurement
1
1
1
24.5
chronotype measurement
1
1
0
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
1
67.1
daytime rest measurement
1
24.5
chronotype measurement
0
1
17.8
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zinc finger and BTB domain containing 5
718482
Mouse
MGI:1924601
230119
Rat
RGD:1307367
298084
Dog
zinc finger and BTB domain containing 5
VGNC:48542
481612
Horse
zinc finger and BTB domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23836]
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zinc finger and BTB domain containing 5
Mouse
Rat
Dog
zinc finger and BTB domain containing 5
Horse
zinc finger and BTB domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23836]
Publication Statistics
PubMed Score 2.35
PubMed score by year
PubTator Score 1.13
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title