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Tdark
ZBTB44
Zinc finger and BTB domain-containing protein 44

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000445008
  • ENSP00000408079
  • ENSG00000196323
  • ENST00000525842
  • ENSP00000433457
  • ENST00000530205
  • ENSP00000434177

Symbol
  • BTBD15
  • ZNF851
  • BTBD15
  • ZNF851
  • HSPC063
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
protein domain
0.85
transcription factor binding site profile
0.74
virus perturbation
0.72
histone modification site profile
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.45   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 146   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.45   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 146   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
WRAP73
Tbio
Novelty:  0.25394934
p_int:  0.999998524
p_ni:  1.12e-7
p_wrong:  0.000001364
Score:  0.185
Data Source:  BioPlex,STRINGDB
CAMK1G
Tchem
Family:  Kinase
Novelty:  0.12524578
p_int:  0.999997728
p_ni:  8.59e-7
p_wrong:  0.000001413
Score:  0.386
Data Source:  BioPlex,STRINGDB
KLHL21
Tbio
Novelty:  0.20694121
p_int:  0.999987326
p_ni:  0.000012674
Score:  0.232
Data Source:  BioPlex,STRINGDB
PSG9
Tbio
Novelty:  0.0426075
p_int:  0.999583482
p_ni:  0.000004653
p_wrong:  0.000411865
Score:  0.163
Data Source:  BioPlex,STRINGDB
SCRIB
Tbio
Novelty:  0.01099525
p_int:  0.995579501
p_ni:  0.004420499
Score:  0.178
Data Source:  BioPlex,STRINGDB
NAE1
Tchem
Novelty:  0.0283623
p_int:  0.989275648
p_ni:  0.010724352
Score:  0.559
Data Source:  BioPlex,STRINGDB
USP7
Tchem
Family:  Enzyme
Novelty:  0.00412878
p_int:  0.979742477
p_ni:  0.020257523
Score:  0.208
Data Source:  BioPlex,STRINGDB
DCAF16
Tdark
Novelty:  0.35666992
p_int:  0.967892814
p_ni:  0.032010327
p_wrong:  0.000096859
Score:  0.173
Data Source:  BioPlex,STRINGDB
UBA3
Tchem
Novelty:  0.03962261
p_int:  0.924153106
p_ni:  0.075846869
p_wrong:  2.6e-8
Score:  0.374
Data Source:  BioPlex,STRINGDB
TRIM11
Tbio
Family:  Enzyme
Novelty:  0.02243955
p_int:  0.755650576
p_ni:  0.238534143
p_wrong:  0.005815281
Score:  0.165
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (14)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cup-to-disc ratio measurement
4
2
5
89.6
intraocular pressure measurement
2
2
2
80
viral load
1
1
1
71.5
1
1
0
1.1
65.5
pulse pressure measurement
1
1
1
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cup-to-disc ratio measurement
5
89.6
intraocular pressure measurement
2
80
viral load
1
71.5
0
1.1
65.5
pulse pressure measurement
1
54.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger and BTB domain containing 44
VGNC:13399
451668
Macaque
zinc finger and BTB domain containing 44
715415
Mouse
MGI:1925123
235132
Rat
RGD:1308984
363035
Dog
zinc finger and BTB domain containing 44
VGNC:48537
489277
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger and BTB domain containing 44
Macaque
zinc finger and BTB domain containing 44
Mouse
Rat
Dog
zinc finger and BTB domain containing 44
Publication Statistics
PubMed Score 1.45
PubMed score by year
PubTator Score 0.36
PubTator score by year
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Related Publications
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PMID
Year
Title