You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
ZBTB40
Zinc finger and BTB domain-containing protein 40

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375647
  • ENSP00000364798
  • ENSG00000184677
  • ENST00000404138
  • ENSP00000384527

Symbol
  • KIAA0478
  • ZNF923
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
1
transcription factor binding site profile
0.93
protein domain
0.92
transcription factor
0.88
histone modification site profile
0.82


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.88   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 164   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.88   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
IER2
Tbio
Novelty:  0.03864806
p_int:  0.999999994
p_ni:  6e-9
p_wrong:  1e-9
Score:  0.224
Data Source:  BioPlex,STRINGDB
NELL2
Tbio
Family:  Enzyme
Novelty:  0.03760438
p_int:  0.999962696
p_ni:  0.000037284
p_wrong:  2e-8
Score:  0.155
Data Source:  BioPlex,STRINGDB
ZNF576
Tdark
Family:  TF
Novelty:  13.18548387
p_int:  0.999946599
p_ni:  0.000043838
p_wrong:  0.000009563
Score:  0.228
Data Source:  BioPlex,STRINGDB
A1BG
Tbio
Novelty:  0.00508743
p_int:  0.99977983
p_ni:  0.000215721
p_wrong:  0.000004449
Score:  0.209
Data Source:  BioPlex,STRINGDB
WRAP73
Tbio
Novelty:  0.25394934
Score:  0.8
Data Source:  STRINGDB
MEGF6
Tdark
Novelty:  0.19604242
Score:  0.749
Data Source:  STRINGDB
ZNF608
Tdark
Novelty:  0.18575706
Score:  0.691
Data Source:  STRINGDB
STARD3NL
Tbio
Novelty:  0.11798896
Score:  0.669
Data Source:  STRINGDB
DCDC1
Tbio
Novelty:  0.21703566
Score:  0.654
Data Source:  STRINGDB
DCDC5
Tdark
Novelty:  0.21703566
Score:  0.654
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (21)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
7
13
98.5
bone density
9
6
10
95
femoral neck bone mineral density
2
2
2
85.1
red blood cell distribution width
4
3
4
80
reticulocyte measurement
3
2
3
76.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
13
98.5
bone density
10
95
femoral neck bone mineral density
2
85.1
red blood cell distribution width
4
80
reticulocyte measurement
3
76.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger and BTB domain containing 40
VGNC:8125
456610
Macaque
zinc finger and BTB domain containing 40
708181
Mouse
MGI:2682254
230848
Rat
RGD:1309866
362635
Dog
zinc finger and BTB domain containing 40
VGNC:48535
487384
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger and BTB domain containing 40
Macaque
zinc finger and BTB domain containing 40
Mouse
Rat
Dog
zinc finger and BTB domain containing 40
Publication Statistics
PubMed Score 5.88
PubMed score by year
PubTator Score 2.08
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title