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Tbio
ZBTB24
Zinc finger and BTB domain-containing protein 24

Protein Summary
Description
May be involved in BMP2-induced transcription. This gene encodes a protein similar to a protein in rodents which is induced by bone morphogenic protein 2 in vitro. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000230122
  • ENSP00000230122
  • ENSG00000112365

Symbol
  • KIAA0441
  • ZNF450
  • BIF1
  • ICF2
  • PATZ2
  • ZNF450
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
virus perturbation
0.85
kinase perturbation
0.81
tissue sample
0.69
cell type or tissue
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 108   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 108   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (66)
NT5C2
Tbio
Family:  Enzyme
Novelty:  0.00758288
p_int:  0.999999921
p_ni:  7.9e-8
Data Source:  BioPlex
KLHL14
Tbio
Novelty:  0.1214402
p_int:  0.999999858
p_ni:  1.4e-7
p_wrong:  2e-9
Data Source:  BioPlex
BACH1
Tbio
Family:  TF
Novelty:  0.04011328
p_int:  0.999998622
p_ni:  0.000001378
Data Source:  BioPlex
MAFG
Tbio
Family:  TF
Novelty:  0.01605125
p_int:  0.999976754
p_ni:  3.62e-7
p_wrong:  0.000022884
Data Source:  BioPlex
ZBTB3
Tdark
Family:  TF
Novelty:  0.34423886
p_int:  0.999976098
p_ni:  0.000021551
p_wrong:  0.000002351
Data Source:  BioPlex
BACH2
Tbio
Family:  TF
Novelty:  0.00932069
p_int:  0.999963247
p_ni:  0.000035396
p_wrong:  0.000001357
Data Source:  BioPlex
ZBTB34
Tdark
Family:  TF
Novelty:  0.5693361
p_int:  0.999888971
p_ni:  0.000101483
p_wrong:  0.000009546
Data Source:  BioPlex
PATZ1
Tbio
Family:  TF
Novelty:  0.02038599
p_int:  0.999283759
p_ni:  0.000716229
p_wrong:  1.1e-8
Data Source:  BioPlex
SATB2
Tbio
Family:  TF
Novelty:  0.00405935
p_int:  0.995902373
p_ni:  0.004096617
p_wrong:  0.00000101
Data Source:  BioPlex
RPL14
Tbio
Novelty:  0.01600377
p_int:  0.993872479
p_ni:  0.00612751
p_wrong:  1.1e-8
Score:  0.286
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
2
2
2
80.6
mosaic loss of chromosome Y measurement
2
1
2
79.9
reticulocyte count
1
1
1
69.5
lymphocyte percentage of leukocytes
1
1
1
56.6
lymphocyte count
2
2
2
56
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
2
80.6
mosaic loss of chromosome Y measurement
2
79.9
reticulocyte count
1
69.5
lymphocyte percentage of leukocytes
1
56.6
lymphocyte count
2
56
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger and BTB domain containing 24
VGNC:7941
740227
Macaque
zinc finger and BTB domain containing 24
700290
Mouse
MGI:3039618
268294
Rat
RGD:1306951
365590
Dog
zinc finger and BTB domain containing 24
VGNC:48528
475021
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger and BTB domain containing 24
Macaque
zinc finger and BTB domain containing 24
Mouse
Rat
Dog
zinc finger and BTB domain containing 24
Publication Statistics
PubMed Score 30.00
PubMed score by year
PubTator Score 20.29
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title