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Tbio
ZBTB12
Zinc finger and BTB domain-containing protein 12

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375525
  • ENSP00000364675
  • ENSG00000206366
  • ENST00000375527
  • ENSP00000364677
  • ENSG00000204366
  • ENST00000432044
  • ENSP00000392328
  • ENSG00000234196
  • ENST00000441555
  • ENSP00000414777
  • ENSG00000237900
  • ENST00000458242
  • ENSP00000391563
  • ENSG00000234852

Symbol
  • C6orf46
  • G10
  • NG35
  • G10
  • Bat9
  • NG35
  • D6S59E
  • C6orf46
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
cell type or tissue
0.68
trait
0.61
cell line
0.59
gene perturbation
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.75   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.75   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (78)
SPTB
Tbio
Novelty:  0.00467504
p_int:  0.999824649
p_ni:  0.000040284
p_wrong:  0.000135067
Score:  0.625
Data Source:  BioPlex,STRINGDB
PRRC2A
Tbio
Novelty:  0.01493149
Score:  0.819
Data Source:  STRINGDB
GPANK1
Tdark
Novelty:  0.20285376
Score:  0.804
Data Source:  STRINGDB
CTNNBL1
Tbio
Novelty:  0.0189038
Score:  0.764
Data Source:  STRINGDB
ABHD16A
Tchem
Family:  Enzyme
Novelty:  0.04797219
Score:  0.755
Data Source:  STRINGDB
PRRT1
Tbio
Novelty:  0.08707857
Score:  0.737
Data Source:  STRINGDB
SKIV2L
Tbio
Family:  Enzyme
Novelty:  0.01108539
Score:  0.715
Data Source:  STRINGDB
DDAH1
Tchem
Family:  Enzyme
Novelty:  0.00354695
Score:  0.663
Data Source:  STRINGDB
EHMT2
Tchem
Family:  Epigenetic
Novelty:  0.00262578
Score:  0.603
Data Source:  STRINGDB
VARS
Tchem
Family:  Enzyme
Novelty:  0.00720227
Score:  0.6
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (340)
Items per page:
1 – 5 of 340
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
9
9
0
1.9
99.3
9
9
0
1.9
99.3
9
9
0
1.9
99.3
9
9
0
1.9
99.3
9
9
0
1.9
99.3
Items per page:
1 – 5 of 340
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.9
99.3
0
1.9
99.3
0
1.9
99.3
0
1.9
99.3
0
1.9
99.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zinc finger and BTB domain containing 12
716846
Mouse
MGI:88133
193736
Rat
RGD:1302958
309613
Dog
zinc finger and BTB domain containing 12
VGNC:48522
481719
Cow
zinc finger and BTB domain containing 12
VGNC:37060
100336034
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zinc finger and BTB domain containing 12
Mouse
Rat
Dog
zinc finger and BTB domain containing 12
Cow
zinc finger and BTB domain containing 12
Publication Statistics
PubMed Score 6.75
PubMed score by year
PubTator Score 5.55
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title