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Tdark
ZAR1L
ZAR1-like protein

Protein Summary
Description
This gene encodes a member of the ZAR1 family that is predominantly expressed in oocytes and early embryos. The protein may function as an RNA regulator in early embryos. [provided by RefSeq, Apr 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000345108
  • ENSP00000344616
  • ENSG00000189167
  • ENST00000533490
  • ENSP00000437289

Symbol
  • ZAR2
  • Z3CXXC7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.68
tissue
0.45
cell line
0.43
phenotype
0.38
biological term
0.33


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.48   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 39   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.48   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 39   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
PXN
Tbio
Novelty:  0.00082031
p_int:  0.999968377
p_ni:  0.000030234
p_wrong:  0.000001388
Data Source:  BioPlex
BCL2L1
Tchem
Novelty:  0.00018414
p_int:  0.999872652
p_ni:  0.00000567
p_wrong:  0.000121677
Data Source:  BioPlex
GLCCI1
Tbio
Novelty:  0.03220482
p_int:  0.99981514
p_ni:  0.000184658
p_wrong:  2.02e-7
Data Source:  BioPlex
SECISBP2L
Tdark
Novelty:  0.03341871
p_int:  0.99961887
p_ni:  0.000188076
p_wrong:  0.000193053
Data Source:  BioPlex
FAM83D
Tbio
Novelty:  0.07381559
p_int:  0.999576482
p_ni:  0.000423518
Data Source:  BioPlex
MIGA1
Tbio
Novelty:  0.08346483
p_int:  0.998828342
p_ni:  0.001171266
p_wrong:  3.91e-7
Data Source:  BioPlex
BCL2L11
Tchem
Novelty:  0.00055914
p_int:  0.998765064
p_ni:  0.001234818
p_wrong:  1.19e-7
Data Source:  BioPlex
HMBOX1
Tbio
Family:  TF
Novelty:  0.02455652
p_int:  0.998496576
p_ni:  0.000043762
p_wrong:  0.001459662
Data Source:  BioPlex
CLUH
Tbio
Novelty:  0.14027296
p_int:  0.995851626
p_ni:  0.004148374
Data Source:  BioPlex
MCL1
Tchem
Novelty:  0.00046181
p_int:  0.985690761
p_ni:  0.014288461
p_wrong:  0.000020778
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations (null)
No disease associations found
GWAS Traits (31)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
22
11
26
96.9
2
2
0
1.8
95.2
apolipoprotein B measurement
3
9
9
94.6
total cholesterol measurement
8
7
10
92.2
2
1
0
1.8
90.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
26
96.9
0
1.8
95.2
apolipoprotein B measurement
9
94.6
total cholesterol measurement
10
92.2
0
1.8
90.6
IDG Resources
No IDG generated resources found
Publication Statistics
PubMed Score 3.48
PubMed score by year
PubTator Score 8.34
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title