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Tbio
YY1AP1
YY1-associated protein 1

Protein Summary
Description
Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication (PubMed:27939641). Enhances transcription activation by YY1 (PubMed:14744866). Plays a role in cell cycle regulation (PubMed:17541814, PubMed:27939641). The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295566
  • ENSP00000295566
  • ENSG00000163374
  • ENST00000311573
  • ENSP00000311138
  • ENST00000347088
  • ENSP00000316079
  • ENST00000355499
  • ENSP00000347686
  • ENST00000359205
  • ENSP00000352134
  • ENST00000361831
  • ENSP00000355298
  • ENST00000368330
  • ENSP00000357314
  • ENST00000368339
  • ENSP00000357323
  • ENST00000368340
  • ENSP00000357324
  • ENST00000404643
  • ENSP00000385390
  • ENST00000407221
  • ENSP00000385791

Symbol
  • HCCA2
  • YY1AP
  • GRNG
  • HCCA1
  • HCCA2
  • YY1AP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.69
transcription factor
0.64
tissue sample
0.63
cell type or tissue
0.61
tissue
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.31   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 134   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.31   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 134   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0