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Tdark
YRDC
YrdC domain-containing protein, mitochondrial

Protein Summary
Description
May regulate the activity of some transporters.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373044
  • ENSP00000362135
  • ENSG00000196449

Symbol
  • DRIP3
  • IRIP
  • IRIP
  • SUA5
  • DRIP3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
histone modification site profile
0.83
ligand (protein) perturbation
0.83
transcription factor perturbation
0.8
cell type or tissue
0.78


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 87.51   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 87.51   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (99)
SPIN1
Tchem
Novelty:  0.00889909
p_int:  0.999936655
p_ni:  0.000063345
Score:  0.85
Data Source:  BioPlex,STRINGDB
SPIN2B
Tchem
Novelty:  0.23202718
p_int:  0.999869996
p_ni:  0.000129998
p_wrong:  6e-9
Score:  0.735
Data Source:  BioPlex,STRINGDB
KHDRBS2
Tbio
Novelty:  0.01986638
p_int:  0.999863096
p_ni:  0.000136901
p_wrong:  2e-9
Score:  0.188
Data Source:  BioPlex,STRINGDB
OSGEPL1
Tbio
Family:  Enzyme
Novelty:  0.13592288
Score:  0.951
Data Source:  STRINGDB
OSGEP
Tbio
Family:  Enzyme
Novelty:  0.0106198
Score:  0.937
Data Source:  STRINGDB
RBBP9
Tchem
Family:  Enzyme
Novelty:  0.08692052
Score:  0.935
Data Source:  STRINGDB
TP53RK
Tbio
Family:  Kinase
Novelty:  0.04302252
Score:  0.881
Data Source:  STRINGDB
TPRKB
Tbio
Novelty:  0.1035085
Score:  0.831
Data Source:  STRINGDB
POLR3K
Tbio
Family:  Enzyme
Novelty:  0.07105011
Score:  0.814
Data Source:  STRINGDB
TRMT5
Tbio
Family:  Enzyme
Novelty:  0.02509765
Score:  0.807
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
1
2
1.1
53.7
mathematical ability
3
2
3
53.2
eosinophil percentage of leukocytes
1
1
1
10.7
eosinophil count
2
1
2
9.4
self reported educational attainment
1
1
1
9.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
1.1
53.7
mathematical ability
3
53.2
eosinophil percentage of leukocytes
1
10.7
eosinophil count
2
9.4
self reported educational attainment
1
9.1
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
yrdC N6-threonylcarbamoyltransferase domain containing
VGNC:10073
456764
Macaque
yrdC N6-threonylcarbamoyltransferase domain containing
100424180
Mouse
MGI:2387201
230734
Rat
RGD:708492
319113
Dog
yrdC N6-threonylcarbamoyltransferase domain containing
VGNC:48502
100855794
Species
Name
OMA
EggNOG
Inparanoid
Chimp
yrdC N6-threonylcarbamoyltransferase domain containing
Macaque
yrdC N6-threonylcarbamoyltransferase domain containing
Mouse
Rat
Dog
yrdC N6-threonylcarbamoyltransferase domain containing
Publication Statistics
PubMed Score 87.51
PubMed score by year
PubTator Score 15.65
PubTator score by year
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Related Publications
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PMID
Year
Title