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Tdark
YIPF4
Protein YIPF4

Protein Summary
Description
Involved in the maintenance of the Golgi structure.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000238831
  • ENSP00000238831
  • ENSG00000119820

Symbol
  • FinGER4
  • Nbla11189
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
histone modification site profile
0.9
small molecule perturbation
0.64
tissue sample
0.6
transcription factor binding site profile
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.8   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 84   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.8   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 84   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (52)
CHRM3
Tclin
Family:  GPCR
Novelty:  0.00849776
p_int:  0.985060761
p_ni:  0.014936763
p_wrong:  0.000002477
Data Source:  BioPlex
VIPR2
Tchem
Family:  GPCR
Novelty:  0.00463802
p_int:  0.98282726
p_ni:  0.017171302
p_wrong:  0.000001438
Data Source:  BioPlex
TMEM63A
Tdark
Family:  IC
Novelty:  0.33131011
p_int:  0.98280861
p_ni:  0.017182704
p_wrong:  0.000008685
Data Source:  BioPlex
SLC7A1
Tbio
Family:  Transporter
Novelty:  0.00197313
p_int:  0.976871227
p_ni:  0.023126177
p_wrong:  0.000002596
Data Source:  BioPlex
RETREG3
Tdark
Novelty:  0.99215801
p_int:  0.975337991
p_ni:  0.024655778
p_wrong:  0.000006231
Score:  0.211
Data Source:  BioPlex,STRINGDB
SLC22A9
Tbio
Family:  Transporter
Novelty:  0.02212992
p_int:  0.971636657
p_ni:  0.028361604
p_wrong:  0.00000174
Data Source:  BioPlex
SPPL2B
Tchem
Family:  Enzyme
Novelty:  0.0274774
p_int:  0.96672184
p_ni:  0.033272627
p_wrong:  0.000005532
Data Source:  BioPlex
KCNA5
Tclin
Family:  IC
Novelty:  0.00182891
p_int:  0.96595319
p_ni:  0.034041429
p_wrong:  0.000005381
Data Source:  BioPlex
YIPF3
Tbio
Novelty:  0.12021667
p_int:  0.958988644
p_ni:  0.041008607
p_wrong:  0.00000275
Score:  0.927
Data Source:  BioPlex,STRINGDB
IPPK
Tbio
Family:  Enzyme
Novelty:  0.02169701
p_int:  0.95587941
p_ni:  0.044118411
p_wrong:  0.000002179
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
interleukin 18 measurement
2
2
2
95.1
testosterone measurement
1
2
2
82.2
sex hormone-binding globulin measurement
4
2
4
74
pallidum volume
1
1
0
5.8
27.3
reticulocyte count
4
1
4
17.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
interleukin 18 measurement
2
95.1
testosterone measurement
2
82.2
sex hormone-binding globulin measurement
4
74
pallidum volume
0
5.8
27.3
reticulocyte count
4
17.7
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
Yip1 domain family member 4
VGNC:2915
743691
Macaque
Yip1 domain family member 4
706819
Mouse
MGI:1915114
67864
Dog
Yip1 domain family member 4
VGNC:48490
475717
Horse
Yip1 domain family member 4
VGNC:51429
100070586
Species
Name
OMA
EggNOG
Inparanoid
Chimp
Yip1 domain family member 4
Macaque
Yip1 domain family member 4
Mouse
Dog
Yip1 domain family member 4
Horse
Yip1 domain family member 4
Publication Statistics
PubMed Score 4.80
PubMed score by year
PubTator Score 13.25
PubTator score by year
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Related Publications
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PMID
Year
Title