Tbio YIPF1 Protein YIPF1

Protein Summary

Uniprot Accession IDs

• Q9Y548
• B2RCM7
• D3DQ40
• Q9NWJ1

Gene Name

• YIPF1

Ensembl ID

• ENST00000072644
• ENSP00000072644
• ENSG00000058799
• ENST00000371399
• ENSP00000360452
• ENST00000464950
• ENSP00000432266

Symbol

• FinGER1
• DJ167A19.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.95
histone modification site profile	0.89
kinase perturbation	0.76
tissue sample	0.6
cell line	0.56

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 138.94   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 87   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 138.94   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Expression Data (0 Tissues)

tutorial

No expression data found

Protein Sequence and Structure

Residue Counts

Protein Sequence

Find Targets by Sequence

Show Full Sequence

ProtVista Viewer

Related Tools (4)

Target Illumination GWAS Analytics (TIGA)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

Go To Tool

GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

Go To Tool

GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

Go To Tool

ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

Go To Tool

Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (39)

Explore Interacting Targets

1 – 10 of 39

• See Interactions on String-DB

YIPF6

Tdark

Novelty:  0.04316252

p_int:  0.9851726

p_ni:  0.014534758

p_wrong:  0.000292643

Score:  0.964

Data Source:  BioPlex,STRINGDB

TPM2

Tbio

Novelty:  0.00406572

p_int:  0.873605631

p_ni:  0.126194615

p_wrong:  0.000199754

Score:  0.211

Data Source:  BioPlex,STRINGDB

TVP23A

Tdark

Novelty:  14.0942837

p_int:  0.869591395

p_ni:  1.1e-8

p_wrong:  0.130408594

Score:  0.303

Data Source:  BioPlex,STRINGDB

FBXO32

Tbio

Novelty:  0.00225437

Score:  0.891

Data Source:  STRINGDB

TRIM63

Tbio

Family:  Enzyme

Novelty:  0.00384819

Score:  0.86

Data Source:  STRINGDB

YIPF3

Tbio

Novelty:  0.12021667

Score:  0.835

Data Source:  STRINGDB

YIPF4

Tdark

Novelty:  0.17862058

Score:  0.814

Data Source:  STRINGDB

FBXO25

Tbio

Novelty:  0.1205608

Score:  0.757

Data Source:  STRINGDB

YIPF5

Tbio

Novelty:  0.08206828

Score:  0.749

Data Source:  STRINGDB

SLC35G1

Tbio

Family:  Transporter

Novelty:  0.06448845

Score:  0.728

Data Source:  STRINGDB

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (9)

Functions (1)

Components (7)

Processes (1)

Find Similar Targets

Items per page:

10

1 – 1 of 1

GO Term	Evidence	Assigned by
Rab GTPase binding	Inferred from Biological aspect of Ancestor (IBA)	GO_Central

Disease Associations (null)

No disease associations found

GWAS Traits (3)

• Explore on Target Illumination GWAS Analytics (TIGA)

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5

1 – 3 of 3

GWAS Trait	EFO ID	Study Count	SNP Count	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
thyroxine measurement	EFO_0005130	1	1	1		81.1
hormone measurement	EFO_0004730	1	1	3		80.4
gut microbiome measurement	EFO_0007874	1	1	0	3.6	24.5

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 3 of 3

GWAS Trait	EFO ID	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
thyroxine measurement	EFO_0005130	1		81.1
hormone measurement	EFO_0004730	3		80.4
gut microbiome measurement	EFO_0007874	0	3.6	24.5

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Find similar targets by:

UniProt Keyword Find Similar Targets

No Header	No Header
Alternative splicing
Complete proteome
Endosome
Glycoprotein
Golgi apparatus
Membrane
Reference proteome
Transmembrane
Transmembrane helix

GWAS Trait Find Similar Targets

No Header	No Header
gut microbiome measurement
hormone measurement
thyroxine measurement

MGI Phenotype Find Similar Targets

No Header	No Header
behavior/neurological phenotype

IDG Resources

No IDG generated resources found

Orthologs (11)

1 – 5 of 11

Species	Name	Source ID	Gene ID	OMA	EggNOG	Inparanoid
Chimp	Yip1 domain family member 1	VGNC:1638	738392
Mouse	Yip1 domain family, member 1	MGI:1915532	230584
Rat	Yip1 domain family, member 1	RGD:735206	298312
Dog	Yip1 domain family member 1	VGNC:48487	489581
Horse	Yip1 domain family member 1	VGNC:25101	100050435

Species	Name	OMA	EggNOG	Inparanoid
Chimp	Yip1 domain family member 1
Mouse	Yip1 domain family, member 1
Rat	Yip1 domain family, member 1
Dog	Yip1 domain family member 1
Horse	Yip1 domain family member 1

Publication Statistics

PubMed Score 138.94

PubMed score by year

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PubTator Score 15.12

PubTator score by year

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Related Publications

Text Mined References (15)

GeneRif Annotations (1)

Items per page:

10

0 of 0

PMID	Year	Title