XPA
DNA repair protein complementing XP-A cells
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.73 | ||
disease | 0.72 | ||
transcription factor perturbation | 0.68 | ||
tissue sample | 0.67 | ||
histone modification site profile | 0.66 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | DNA Repair | ||||
Reactome | Dual Incision in GG-NER | ||||
Reactome | Dual incision in TC-NER | ||||
Reactome | Formation of Incision Complex in GG-NER | ||||
Reactome | Formation of TC-NER Pre-Incision Complex | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
DNA Repair | ||||
Dual Incision in GG-NER | ||||
Dual incision in TC-NER | ||||
Formation of Incision Complex in GG-NER | ||||
Formation of TC-NER Pre-Incision Complex | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
4 | 4 | 1 | 1.3 | 98.1 | |||||
thyroid carcinoma | 6 | 3 | 0 | 1.7 | 96.4 | ||||
thyroid stimulating hormone measurement | 4 | 4 | 4 | 89.8 | |||||
autoimmune thyroid disease | 1 | 1 | 0 | 1.3 | 87.4 | ||||
Thyroid preparation use measurement | 1 | 1 | 1 | 86.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
1 | 1.3 | 98.1 | |||||
thyroid carcinoma | 0 | 1.7 | 96.4 | ||||
thyroid stimulating hormone measurement | 4 | 89.8 | |||||
autoimmune thyroid disease | 0 | 1.3 | 87.4 | ||||
Thyroid preparation use measurement | 1 | 86.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | XPA, DNA damage recognition and repair factor | VGNC:10482 | 747191 | |||||
Macaque | XPA, DNA damage recognition and repair factor | 715705 | ||||||
Mouse | MGI:99135 | 22590 | ||||||
Rat | RGD:1308769 | 298074 | ||||||
Dog | XPA, DNA damage recognition and repair factor | VGNC:48455 | 481623 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | XPA, DNA damage recognition and repair factor | |||||
Macaque | XPA, DNA damage recognition and repair factor | |||||
Mouse | ||||||
Rat | ||||||
Dog | XPA, DNA damage recognition and repair factor | |||||
PMID | Year | Title |
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