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Tbio
XIRP1
Xin actin-binding repeat-containing protein 1

Protein Summary
Description
Protects actin filaments from depolymerization. The protein encoded by this gene is a striated muscle protein and belongs to the Xin actin-binding repeat-containing protein (XIRP) family. The protein functions to protect actin filaments during depolymerization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000340369
  • ENSP00000343140
  • ENSG00000168334
  • ENST00000396251
  • ENSP00000379550
  • ENST00000421646
  • ENSP00000391645

Symbol
  • CMYA1
  • XIN
  • Xin
  • CMYA1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.99
tissue sample
0.64
cell type or tissue
0.55
cell line
0.44
cellular component
0.42


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.93   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.93   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0