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Tdark
XG
Glycoprotein Xg

Protein Summary
Description
This gene encodes the XG blood group antigen, and is located at the pseudoautosomal boundary on the short (p) arm of chromosome X. The three 5' exons reside in the pseudoautosomal region and the remaining exons within the X-specific end. A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary. It is transcribed, but not expected to make a Y-chromosome specific gene product. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000381174
  • ENSP00000370566
  • ENSG00000124343
  • ENST00000644266
  • ENSP00000494087

Symbol
  • PBDX
  • PBDX
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.98
cell type or tissue
0.8
disease
0.66
tissue sample
0.57
cell line
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.41   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 42   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.41   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 42   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
CD99
Tbio
Novelty:  0.00229439
Score:  0.8
Data Source:  STRINGDB
TRAPPC2B
Tdark
Novelty:  0.03942393
Score:  0.642
Data Source:  STRINGDB
ASMT
Tbio
Family:  Enzyme
Novelty:  0.00251977
Score:  0.623
Data Source:  STRINGDB
TRAPPC2
Tbio
Novelty:  0.02016231
Score:  0.623
Data Source:  STRINGDB
CRYZL1
Tbio
Family:  Enzyme
Novelty:  0.04435286
Score:  0.616
Data Source:  STRINGDB
CD99L2
Tbio
Novelty:  0.11041595
Score:  0.585
Data Source:  STRINGDB
ARSD
Tbio
Family:  Enzyme
Novelty:  0.00680724
Score:  0.55
Data Source:  STRINGDB
STS
Tchem
Family:  Enzyme
Novelty:  0.00324549
Score:  0.547
Data Source:  STRINGDB
ARSH
Tbio
Family:  Enzyme
Novelty:  0.03202479
Score:  0.547
Data Source:  STRINGDB
MAOB
Tclin
Family:  Enzyme
Novelty:  0.00030366
Score:  0.54
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
1
1
7.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
7.6
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
Xg glycoprotein (Xg blood group)
VGNC:1185
100615832
Macaque
Xg blood group
705377
Dog
Xg glycoprotein (Xg blood group)
VGNC:48449
609839
Horse
Xg glycoprotein (Xg blood group)
VGNC:25066
100629971
Cow
Xg blood group [Source:HGNC Symbol;Acc:HGNC:12806]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
Xg glycoprotein (Xg blood group)
Macaque
Xg blood group
Dog
Xg glycoprotein (Xg blood group)
Horse
Xg glycoprotein (Xg blood group)
Cow
Xg blood group [Source:HGNC Symbol;Acc:HGNC:12806]
Publication Statistics
PubMed Score 9.41
PubMed score by year
PubTator Score 39.67
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title