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Tdark
WDR89
WD repeat-containing protein 89

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000267522
  • ENSP00000267522
  • ENSG00000140006
  • ENST00000394942
  • ENSP00000378399
  • ENST00000620954
  • ENSP00000480112

Symbol
  • C14orf150
  • MSTP050
  • C14orf150
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.89
kinase perturbation
0.84
transcription factor binding site profile
0.7
transcription factor perturbation
0.68
tissue
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.66   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 101   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.66   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
NOL8
Tbio
Novelty:  0.28065454
p_int:  0.999990851
p_ni:  0.000009148
Score:  0.837
Data Source:  BioPlex,STRINGDB
RPL10A
Tbio
Novelty:  0.01747453
p_int:  0.999677283
p_ni:  0.000322712
p_wrong:  5e-9
Score:  0.536
Data Source:  BioPlex,STRINGDB
TFPI2
Tbio
Novelty:  0.00475383
p_int:  0.998004848
p_ni:  0.001619049
p_wrong:  0.000376102
Data Source:  BioPlex
CCT2
Tbio
Novelty:  0.01967139
p_int:  0.997633411
p_ni:  0.00226053
p_wrong:  0.000106059
Data Source:  BioPlex
IGHMBP2
Tbio
Novelty:  0.01054517
p_int:  0.995189514
p_ni:  0.004810485
p_wrong:  1e-9
Score:  0.203
Data Source:  BioPlex,STRINGDB
SIGLEC7
Tchem
Novelty:  0.01496432
p_int:  0.994604217
p_ni:  0.004955784
p_wrong:  0.00044
Score:  0.379
Data Source:  BioPlex,STRINGDB
HMGA1
Tbio
Family:  TF
Novelty:  0.00185669
p_int:  0.840107853
p_ni:  0.032435088
p_wrong:  0.127457059
Data Source:  BioPlex
RRS1
Tbio
Novelty:  0.01643671
Score:  0.827
Data Source:  STRINGDB
WDR12
Tbio
Novelty:  0.03409059
Score:  0.779
Data Source:  STRINGDB
WDR74
Tbio
Novelty:  0.07119796
Score:  0.673
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
17.8
IDG Resources
No IDG generated resources found
Orthologs (16)
1 – 5 of 16
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
WD repeat domain 89
VGNC:12427
452963
Macaque
WD repeat domain 89
706314
Mouse
MGI:1919588
72338
Rat
RGD:1307393
314243
Dog
WD repeat domain 89
VGNC:48396
100684919
Species
Name
OMA
EggNOG
Inparanoid
Chimp
WD repeat domain 89
Macaque
WD repeat domain 89
Mouse
Rat
Dog
WD repeat domain 89
Publication Statistics
PubMed Score 0.66
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title