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Tdark
WDR47
WD repeat-containing protein 47

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361054
  • ENSP00000354339
  • ENSG00000085433
  • ENST00000369962
  • ENSP00000358979
  • ENST00000369965
  • ENSP00000358982
  • ENST00000400794
  • ENSP00000383599

Symbol
  • KIAA0893
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
kinase perturbation
0.71
transcription factor binding site profile
0.69
transcription factor
0.64
microRNA
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.39   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 43   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.39   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 43   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
RHEX
Tbio
Novelty:  0.20957256
p_int:  0.999999995
p_ni:  5e-9
Score:  0.209
Data Source:  BioPlex,STRINGDB
ANGPTL4
Tbio
Novelty:  0.00237867
p_int:  0.999999989
p_ni:  1.1e-8
Score:  0.188
Data Source:  BioPlex,STRINGDB
FAIM
Tbio
Novelty:  0.02606594
p_int:  0.999999977
p_ni:  2.3e-8
Data Source:  BioPlex
TEX45
Tdark
Novelty:  5.55785981
p_int:  0.999998215
p_ni:  0.000001783
p_wrong:  2e-9
Score:  0.165
Data Source:  BioPlex,STRINGDB
PLB1
Tbio
Family:  Enzyme
Novelty:  0.01628403
p_int:  0.998499346
p_ni:  0.001500653
Score:  0.187
Data Source:  BioPlex,STRINGDB
COBL
Tbio
Novelty:  0.01903038
p_int:  0.997061485
p_ni:  0.002938286
p_wrong:  2.29e-7
Score:  0.19
Data Source:  BioPlex,STRINGDB
POC1B
Tbio
Novelty:  0.09023863
p_int:  0.996231052
p_ni:  0.003768948
Score:  0.185
Data Source:  BioPlex,STRINGDB
FAM163A
Tbio
Novelty:  0.1944453
p_int:  0.994575588
p_ni:  0.005424412
Score:  0.221
Data Source:  BioPlex,STRINGDB
VWA2
Tbio
Novelty:  0.05840015
p_int:  0.933761195
p_ni:  0.066084918
p_wrong:  0.000153887
Score:  0.239
Data Source:  BioPlex,STRINGDB
RHPN1
Tbio
Novelty:  0.05722992
p_int:  0.858860608
p_ni:  0.139965322
p_wrong:  0.00117407
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein B measurement
2
3
3
87.5
alkaline phosphatase measurement
2
2
1
7.1
82.1
low density lipoprotein cholesterol measurement
2
2
2
77.4
leukocyte count
1
1
1
65.2
very low density lipoprotein cholesterol measurement
5
2
5
29.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein B measurement
3
87.5
alkaline phosphatase measurement
1
7.1
82.1
low density lipoprotein cholesterol measurement
2
77.4
leukocyte count
1
65.2
very low density lipoprotein cholesterol measurement
5
29.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
WD repeat domain 47
VGNC:1641
457082
Macaque
WD repeat domain 47
696942
Mouse
MGI:2139593
99512
Rat
RGD:1309181
310785
Dog
WD repeat domain 47
VGNC:48370
490126
Species
Name
OMA
EggNOG
Inparanoid
Chimp
WD repeat domain 47
Macaque
WD repeat domain 47
Mouse
Rat
Dog
WD repeat domain 47
Publication Statistics
PubMed Score 4.39
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title