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Tdark
VWA5B2
von Willebrand factor A domain-containing protein 5B2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000426955
  • ENSP00000398688
  • ENSG00000145198
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.64
cell type or tissue
0.63
cell line
0.6
histone modification site profile
0.59
protein complex
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.52   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 46   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.52   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
RAB3A
Tbio
Family:  Enzyme
Novelty:  0.0043532
p_int:  0.943977832
p_ni:  1e-8
p_wrong:  0.056022158
Score:  0.381
Data Source:  BioPlex,STRINGDB
LRP3
Tbio
Novelty:  0.09085132
Score:  0.772
Data Source:  STRINGDB
PACSIN1
Tbio
Family:  Enzyme
Novelty:  0.01482925
Score:  0.752
Data Source:  STRINGDB
SH3RF3
Tbio
Novelty:  0.3995352
Score:  0.682
Data Source:  STRINGDB
EPN2
Tbio
Novelty:  0.06405828
Score:  0.647
Data Source:  STRINGDB
MAP6D1
Tdark
Novelty:  0.07326913
Score:  0.636
Data Source:  STRINGDB
FAM131A
Tdark
Novelty:  1.91916255
Score:  0.623
Data Source:  STRINGDB
CAMK2N2
Tbio
Family:  Enzyme
Novelty:  0.04646909
Score:  0.588
Data Source:  STRINGDB
CRLF1
Tbio
Novelty:  0.02127014
Score:  0.581
Data Source:  STRINGDB
ALG3
Tbio
Family:  Enzyme
Novelty:  0.0159047
Score:  0.57
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (14)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
4
2
4
92.2
mathematical ability
4
4
6
75.1
daytime rest measurement
1
1
1
74.8
body mass index
2
2
2
67.8
age at menarche
1
1
1
53.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
4
92.2
mathematical ability
6
75.1
daytime rest measurement
1
74.8
body mass index
2
67.8
age at menarche
1
53.7
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
von Willebrand factor A domain containing 5B2
VGNC:14629
460885
Macaque
von Willebrand factor A domain containing 5B2
702960
Mouse
MGI:2681859
328643
Rat
RGD:1564491
303812
Dog
von Willebrand factor A domain containing 5B2
VGNC:48323
488104
Species
Name
OMA
EggNOG
Inparanoid
Chimp
von Willebrand factor A domain containing 5B2
Macaque
von Willebrand factor A domain containing 5B2
Mouse
Rat
Dog
von Willebrand factor A domain containing 5B2
Publication Statistics
PubMed Score 0.52
PubMed score by year
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Related Publications
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PMID
Year
Title