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Tdark
VSIG8
V-set and immunoglobulin domain-containing protein 8

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368100
  • ENSP00000357080
  • ENSG00000243284

Symbol
  • C1orf204
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.71
cell type or tissue
0.65
gene perturbation
0.59
tissue
0.45
cellular component
0.41


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.95   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.95   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (75)
FBXL4
Tbio
Novelty:  0.04286856
p_int:  0.999951997
p_ni:  0.000047989
p_wrong:  1.4e-8
Data Source:  BioPlex
IL31RA
Tbio
Novelty:  0.00737445
p_int:  0.999949358
p_ni:  0.000050642
Data Source:  BioPlex
MRPL38
Tdark
Novelty:  0.71587283
p_int:  0.99991374
p_ni:  0.00008626
Data Source:  BioPlex
RAB11B
Tbio
Family:  Enzyme
Novelty:  0.00557558
p_int:  0.999823916
p_ni:  0.000176084
Data Source:  BioPlex
LAIR2
Tbio
Novelty:  0.06117644
p_int:  0.999819137
p_ni:  0.000180863
Data Source:  BioPlex
KIF3A
Tbio
Novelty:  0.00555124
p_int:  0.999699826
p_ni:  0.000300173
Data Source:  BioPlex
RPN2
Tbio
Family:  Enzyme
Novelty:  0.01796569
p_int:  0.999444602
p_ni:  0.000555398
Data Source:  BioPlex
ELOA2
Tdark
Family:  Enzyme
Novelty:  0.7420148
p_int:  0.999308471
p_ni:  0.000690696
p_wrong:  8.33e-7
Data Source:  BioPlex
OR51E2
Tchem
Family:  oGPCR
Novelty:  0.02435259
p_int:  0.99911772
p_ni:  0.00088228
Data Source:  BioPlex
GDF5
Tbio
Novelty:  0.00218118
p_int:  0.998923574
p_ni:  0.001076426
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
C-reactive protein measurement
2
6
7
98.2
mean platelet volume
3
1
3
84.7
bilirubin measurement
1
1
1
42.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
C-reactive protein measurement
7
98.2
mean platelet volume
3
84.7
bilirubin measurement
1
42.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
V-set and immunoglobulin domain containing 8
VGNC:10893
745370
Macaque
V-set and immunoglobulin domain containing 8 [Source:HGNC Symbol;Acc:HGNC:32063]
Mouse
MGI:3642995
240916
Rat
RGD:1562464
289236
Dog
V-set and immunoglobulin domain containing 8
100683194
Species
Name
OMA
EggNOG
Inparanoid
Chimp
V-set and immunoglobulin domain containing 8
Macaque
V-set and immunoglobulin domain containing 8 [Source:HGNC Symbol;Acc:HGNC:32063]
Mouse
Rat
Dog
V-set and immunoglobulin domain containing 8
Publication Statistics
PubMed Score 0.95
PubMed score by year
PubTator Score 1.10
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title