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Tdark
VSIG10
V-set and immunoglobulin domain-containing protein 10

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000359236
  • ENSP00000352172
  • ENSG00000176834
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.88
histone modification site profile
0.85
protein domain
0.85
gene perturbation
0.76
microRNA
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.36   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.36   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (11)
ST3GAL5
Tbio
Family:  Enzyme
Novelty:  0.01407498
Score:  0.548
Data Source:  STRINGDB
ITPRIPL2
Tdark
Novelty:  1.92099276
Score:  0.546
Data Source:  STRINGDB
DHRS13
Tdark
Family:  Enzyme
Novelty:  3.32504512
Score:  0.526
Data Source:  STRINGDB
PTGFRN
Tbio
Novelty:  0.02271483
Score:  0.525
Data Source:  STRINGDB
CELSR1
Tbio
Family:  GPCR
Novelty:  0.02076192
Score:  0.512
Data Source:  STRINGDB
ZHX3
Tbio
Family:  TF
Novelty:  0.13068792
Score:  0.496
Data Source:  STRINGDB
CD109
Tbio
Novelty:  0.01280272
Score:  0.484
Data Source:  STRINGDB
TSPAN8
Tbio
Novelty:  0.01536012
Score:  0.473
Data Source:  STRINGDB
WSB2
Tbio
Novelty:  0.03939755
Score:  0.447
Data Source:  STRINGDB
FAM198B
Tbio
Novelty:  0.16692868
Score:  0.446
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
type 2 diabetes mellitus
6
2
4
1.1
87.1
neuroimaging measurement
18
6
18
64.9
body mass index
3
3
3
61.5
body weight
1
1
1
43.2
Drugs used in diabetes use measurement
1
1
1
33.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
type 2 diabetes mellitus
4
1.1
87.1
neuroimaging measurement
18
64.9
body mass index
3
61.5
body weight
1
43.2
Drugs used in diabetes use measurement
1
33.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
V-set and immunoglobulin domain containing 10
VGNC:13493
452290
Mouse
MGI:2448533
231668
Rat
RGD:1565800
304529
Dog
V-set and immunoglobulin domain containing 10
VGNC:48306
486292
Horse
V-set and immunoglobulin domain containing 10
VGNC:24942
100054850
Species
Name
OMA
EggNOG
Inparanoid
Chimp
V-set and immunoglobulin domain containing 10
Mouse
Rat
Dog
V-set and immunoglobulin domain containing 10
Horse
V-set and immunoglobulin domain containing 10
Publication Statistics
PubMed Score 0.36
PubMed score by year
PubTator Score 0.33
PubTator score by year
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Related Publications
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PMID
Year
Title