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Tbio
VNN3
Vascular non-inflammatory molecule 3

Protein Summary
Description
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. This gene is the central gene in a cluster of three vanin genes on chromosome 6q23-q24. Extensive alternative splicing has been described; the two most common variants are represented as RefSeqs. [provided by RefSeq, Apr 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000275223
  • ENSP00000443073
  • ENSG00000093134
  • ENST00000367927
  • ENSP00000438024
  • ENST00000392393
  • ENSP00000441182
  • ENST00000414302
  • ENSP00000444505
  • ENST00000417437
  • ENSP00000463583
  • ENST00000423615
  • ENSP00000443901
  • ENST00000425515
  • ENSP00000439449
  • ENST00000427187
  • ENSP00000444491
  • ENST00000509351
  • ENSP00000464241
  • ENST00000519686
  • ENSP00000438175

Symbol
  • HSA238982
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.76
tissue sample
0.76
cell line
0.61
virus perturbation
0.55
metabolite
0.45


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.85   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 78   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.85   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 78   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0