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Tbio
VASN
Vasorin

Protein Summary
Description
May act as an inhibitor of TGF-beta signaling.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000304735
  • ENSP00000306864
  • ENSG00000168140
  • ENST00000622615
  • ENSP00000481884
  • ENSG00000274334

Symbol
  • SLITL2
  • SLITL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.97
kinase perturbation
0.84
small molecule perturbation
0.73
tissue sample
0.71
cellular component
0.69


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.28   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 182   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.28   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 182   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (68)
JAG2
Tbio
Novelty:  0.00176158
p_int:  0.99998421
p_ni:  0.000015567
p_wrong:  2.23e-7
Score:  0.164
Data Source:  BioPlex,STRINGDB
ABCD1
Tbio
Family:  Transporter
Novelty:  0.0067013
p_int:  0.999979761
p_ni:  0.000020238
p_wrong:  1e-9
Score:  0.173
Data Source:  BioPlex,STRINGDB
TAF12
Tbio
Novelty:  0.04352637
p_int:  0.99996237
p_ni:  0.000037628
p_wrong:  1e-9
Data Source:  BioPlex
CNPY3
Tbio
Novelty:  0.11473132
p_int:  0.999867522
p_ni:  0.000132478
Data Source:  BioPlex
THADA
Tbio
Novelty:  0.06983966
p_int:  0.999712967
p_ni:  0.000287033
Data Source:  BioPlex
NOTCH2
Tchem
Novelty:  0.00195617
p_int:  0.997817037
p_ni:  0.002182963
Score:  0.18
Data Source:  BioPlex,STRINGDB
XPO4
Tbio
Novelty:  0.01507446
p_int:  0.997566497
p_ni:  0.002433502
Data Source:  BioPlex
TMX4
Tdark
Novelty:  0.2628295
p_int:  0.997339875
p_ni:  0.002660125
Data Source:  BioPlex
AP3B1
Tbio
Novelty:  0.03117931
p_int:  0.995339928
p_ni:  0.004660072
Data Source:  BioPlex
STK11IP
Tdark
Family:  Enzyme
Novelty:  0.2856954
p_int:  0.992172354
p_ni:  0.007827646
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (36)
Items per page:
1 – 5 of 36
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
10
16
26
95.7
BMI-adjusted waist-hip ratio
10
16
26
95.7
BMI-adjusted hip circumference
3
10
11
92.4
BMI-adjusted hip circumference
3
10
11
92.4
hip circumference
1
5
5
87.5
Items per page:
1 – 5 of 36
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
26
95.7
BMI-adjusted waist-hip ratio
26
95.7
BMI-adjusted hip circumference
11
92.4
BMI-adjusted hip circumference
11
92.4
hip circumference
5
87.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
vasorin
VGNC:51618
748122
Mouse
MGI:2177651
246154
Rat
RGD:1598149
679921
Dog
vasorin
VGNC:54089
100688709
Horse
vasorin
VGNC:52459
100629909
Species
Name
OMA
EggNOG
Inparanoid
Chimp
vasorin
Mouse
Rat
Dog
vasorin
Horse
vasorin
Publication Statistics
PubMed Score 29.28
PubMed score by year
PubTator Score 13.44
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title