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Tchem
UTS2R
Urotensin-2 receptor

Protein Summary
Description
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000313135
  • ENSP00000323516
  • ENSG00000181408

Symbol
  • GPR14
  • UTR
  • UTR2
  • GPR14
  • UR-2-R
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.72
gene perturbation
0.7
ligand (chemical)
0.61
biological term
0.52
cell line
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 111.84   (req: < 5)
Gene RIFs: 31   (req: <= 3)
Antibodies: 225   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 111.84   (req: >= 5)
Gene RIFs: 31   (req: > 3)
Antibodies: 225   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 230
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0