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Tbio
UTP11
Probable U3 small nucleolar RNA-associated protein 11

Protein Summary
Description
Involved in nucleolar processing of pre-18S ribosomal RNA.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373014
  • ENSP00000362105
  • ENSG00000183520

Symbol
  • UTP11L
  • CGI94
  • CGI-94
  • UTP11L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.23   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 115   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.23   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (297)
APP
Tchem
Novelty:  0.00008964
p_int:  0.999984401
p_ni:  0.000014313
p_wrong:  0.000001286
Data Source:  BioPlex
IKZF5
Tbio
Family:  TF
Novelty:  0.36596327
p_int:  0.99983947
p_ni:  0.000052628
p_wrong:  0.000107902
Data Source:  BioPlex
MRPL34
Tdark
Novelty:  1.17388411
p_int:  0.999691257
p_ni:  0.000210801
p_wrong:  0.000097942
Score:  0.234
Data Source:  BioPlex,STRINGDB
KLHL41
Tbio
Novelty:  0.03973182
p_int:  0.999620533
p_ni:  0.000001121
p_wrong:  0.000378346
Score:  0.513
Data Source:  BioPlex,STRINGDB
THNSL1
Tdark
Family:  Enzyme
Novelty:  1.98275016
p_int:  0.999511919
p_ni:  0.000481876
p_wrong:  0.000006205
Score:  0.261
Data Source:  BioPlex,STRINGDB
CRNN
Tbio
Novelty:  0.01648731
p_int:  0.928135195
p_ni:  0.071853113
p_wrong:  0.000011692
Score:  0.209
Data Source:  BioPlex,STRINGDB
UTP18
Tdark
Novelty:  0.1719213
Score:  0.999
Data Source:  STRINGDB
WDR46
Tbio
Novelty:  0.19307408
Score:  0.999
Data Source:  STRINGDB
UTP3
Tbio
Novelty:  0.06371711
Score:  0.999
Data Source:  STRINGDB
NOP14
Tbio
Novelty:  0.08903014
Score:  0.998
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
Major pathway of rRNA processing in the nucleolus and cytosol (R-HSA-6791226)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Major pathway of rRNA processing in the nucleolus and cytosol
Reactome
Metabolism of RNA
Reactome
rRNA modification in the nucleus and cytosol
Reactome
rRNA processing
Reactome
rRNA processing in the nucleus and cytosol
Name
Explore in Pharos
Explore in Source
Major pathway of rRNA processing in the nucleolus and cytosol
Metabolism of RNA
rRNA modification in the nucleus and cytosol
rRNA processing
rRNA processing in the nucleus and cytosol
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations ()
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
2
4
63.7
body height
1
1
1
54.4
pulse pressure measurement
1
1
2
50.6
Thyroid preparation use measurement
1
1
1
48.5
2
2
0
1.1
48.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
63.7
body height
1
54.4
pulse pressure measurement
2
50.6
Thyroid preparation use measurement
1
48.5
0
1.1
48.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (16)
1 – 5 of 16
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
UTP11, small subunit processome component
VGNC:14850
456769
Macaque
UTP11, small subunit processome component
715363
Mouse
MGI:1914455
67205
Rat
RGD:621412
313581
Dog
UTP11, small subunit processome component
VGNC:48208
475325
Species
Name
OMA
EggNOG
Inparanoid
Chimp
UTP11, small subunit processome component
Macaque
UTP11, small subunit processome component
Mouse
Rat
Dog
UTP11, small subunit processome component
Publication Statistics
PubMed Score 4.23
PubMed score by year
PubTator Score 1.96
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title