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Tdark
USP17L11
Ubiquitin carboxyl-terminal hydrolase 17-like protein 11

Protein Summary
Description
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000457736
  • ENSP00000400880
  • ENSG00000233136
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.58
tissue
0.58
biological process
0.4
molecular function
0.38
cell line
0.37


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.01   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 3   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.01   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 3   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (33)
USP17L2
Tbio
Family:  Enzyme
Novelty:  0.06585454
Score:  0.915
Data Source:  STRINGDB
USP17L22
Tdark
Family:  Enzyme
Novelty:  32
Score:  0.913
Data Source:  STRINGDB
USP17L20
Tdark
Family:  Enzyme
Novelty:  6
Score:  0.907
Data Source:  STRINGDB
USP17L18
Tdark
Family:  Enzyme
Novelty:  122
Score:  0.906
Data Source:  STRINGDB
USP17L4
Tdark
Family:  Enzyme
Novelty:  11.52
Score:  0.902
Data Source:  STRINGDB
RCE1
Tchem
Family:  Enzyme
Novelty:  0.01209847
Score:  0.901
Data Source:  STRINGDB
USP17L19
Tdark
Family:  Enzyme
Score:  0.9
Data Source:  STRINGDB
USP17L15
Tdark
Family:  Enzyme
Score:  0.9
Data Source:  STRINGDB
DDX58
Tbio
Family:  Enzyme
Novelty:  0.00080099
Score:  0.9
Data Source:  STRINGDB
IFIH1
Tbio
Family:  Enzyme
Novelty:  0.00111499
Score:  0.9
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Deubiquitination (R-HSA-5688426)

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Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Deubiquitination
Reactome
Metabolism of proteins
Reactome
Post-translational protein modification
Reactome
Ub-specific processing proteases
Name
Explore in Pharos
Explore in Source
Deubiquitination
Metabolism of proteins
Post-translational protein modification
Ub-specific processing proteases
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.01
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title