UNC13B
Protein unc-13 homolog B
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.95 | ||
protein domain | 0.92 | ||
metabolite | 0.82 | ||
biological process | 0.77 | ||
cellular component | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Acetylcholine Neurotransmitter Release Cycle | ||||
Reactome | Dopamine Neurotransmitter Release Cycle | ||||
Reactome | Glutamate Neurotransmitter Release Cycle | ||||
Reactome | Neuronal System | ||||
Reactome | Neurotransmitter release cycle | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Acetylcholine Neurotransmitter Release Cycle | ||||
Dopamine Neurotransmitter Release Cycle | ||||
Glutamate Neurotransmitter Release Cycle | ||||
Neuronal System | ||||
Neurotransmitter release cycle | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | ParkinsonsUK-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | ParkinsonsUK-UCL | |||
Non-traceable Author Statement (NAS) | ParkinsonsUK-UCL | |||
Non-traceable Author Statement (NAS) | ParkinsonsUK-UCL | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
platelet count | 1 | 1 | 1 | 57.8 | |||||
mean platelet volume | 1 | 1 | 1 | 53.7 | |||||
mean corpuscular volume | 1 | 1 | 1 | 33 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 29.8 | |||||
mean corpuscular hemoglobin concentration | 1 | 1 | 1 | 12.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
platelet count | 1 | 57.8 | |||||
mean platelet volume | 1 | 53.7 | |||||
mean corpuscular volume | 1 | 33 | |||||
mean reticulocyte volume | 1 | 29.8 | |||||
mean corpuscular hemoglobin concentration | 1 | 12.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | unc-13 homolog B | 697393 | ||||||
Mouse | MGI:1342278 | 22249 | ||||||
Rat | RGD:619723 | 64830 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | unc-13 homolog B | |||||
Mouse | ||||||
Rat | ||||||
PMID | Year | Title |
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