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Tbio
UHRF1BP1
UHRF1-binding protein 1

Protein Summary
Description
May act as a negative regulator of cell growth.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000192788
  • ENSP00000192788
  • ENSG00000065060

Symbol
  • C6orf107
  • ICBP90
  • C6orf107
  • dJ349A12.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.88
microRNA
0.74
cell line
0.72
cellular component
0.64
transcription factor binding site profile
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.69   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 53   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.69   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (60)
RASEF
Tbio
Novelty:  0.08877022
p_int:  0.999999247
p_ni:  7.36e-7
p_wrong:  1.7e-8
Data Source:  BioPlex
EPB41L5
Tbio
Novelty:  0.0391959
p_int:  0.999998324
p_ni:  0.000001563
p_wrong:  1.14e-7
Data Source:  BioPlex
STK16
Tchem
Family:  Kinase
Novelty:  0.01499094
p_int:  0.999824893
p_ni:  0.000175107
Score:  0.188
Data Source:  BioPlex,STRINGDB
CREB3L1
Tbio
Family:  TF
Novelty:  0.02295608
p_int:  0.999703414
p_ni:  0.000296585
p_wrong:  1e-9
Score:  0.228
Data Source:  BioPlex,STRINGDB
RAB30
Tbio
Family:  Enzyme
Novelty:  0.1262404
p_int:  0.999319369
p_ni:  0.000680631
Score:  0.221
Data Source:  BioPlex,STRINGDB
FIS1
Tbio
Novelty:  0.0033607
p_int:  0.998880287
p_ni:  0.001119712
p_wrong:  1e-9
Data Source:  BioPlex
CREB3
Tbio
Family:  TF
Novelty:  0.00424318
p_int:  0.997326129
p_ni:  0.002673871
p_wrong:  1e-9
Score:  0.261
Data Source:  BioPlex,STRINGDB
LINC01587
Tdark
Novelty:  0.48128342
p_int:  0.984646406
p_ni:  0.015353509
p_wrong:  8.4e-8
Score:  0.175
Data Source:  BioPlex,STRINGDB
CALML3
Tbio
Novelty:  0.0336689
p_int:  0.978366474
p_ni:  0.021633516
p_wrong:  1.1e-8
Data Source:  BioPlex
FAM131B
Tdark
Novelty:  0.3424123
p_int:  0.958509028
p_ni:  0.041490971
p_wrong:  1e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (42)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
7
7
8
98.5
BMI-adjusted hip circumference
4
12
16
96.3
high density lipoprotein cholesterol measurement
7
3
7
90.9
6
4
0
1.2
90.5
BMI-adjusted waist-hip ratio
3
4
6
90.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
8
98.5
BMI-adjusted hip circumference
16
96.3
high density lipoprotein cholesterol measurement
7
90.9
0
1.2
90.5
BMI-adjusted waist-hip ratio
6
90.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
UHRF1 binding protein 1
VGNC:3780
462630
Macaque
UHRF1 binding protein 1
718719
Mouse
MGI:3041238
224648
Rat
RGD:1307264
309637
Dog
UHRF1 binding protein 1
VGNC:48124
481752
Species
Name
OMA
EggNOG
Inparanoid
Chimp
UHRF1 binding protein 1
Macaque
UHRF1 binding protein 1
Mouse
Rat
Dog
UHRF1 binding protein 1
Publication Statistics
PubMed Score 6.69
PubMed score by year
PubTator Score 16.18
PubTator score by year
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Related Publications
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PMID
Year
Title